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Within Reason
It has long been a central conviction of western humanistic thought that reason is the most godlike of human traits, and that it makes us unique among animals. Yet if reason directs what we do, why is human behavior so often violent, irrational and disastrous? In Within Reason, leading neurologist Donald B. Calne investigates the phenomenon of rationality from an astonishingly wide array of scientific, sociological, and philosophical perspectives--and shows that although reason evolved as a crucial tool for human survival, it is an aspect of mind and brain which has no inherent moral or spiritual qualities and one whose relationship to our thoughts and actions may not be as central as we want to believe. Learned, lucid, and always illuminating, Within Reason brings together the latest developments in the science of mind with some of the most enduring questions of Western thought.
NINDS at 50
None
National Health Directory
A guide to federal, congressional, state, county and city health agencies and officials. Includes congressional standard, select, and joint committees, key health subcommittees, and delegations. Also includes federal health agencies, and state county and city health officials.
DHEW Publication
None
Scientific Directory and Annual Bibliography
Each issue lists papers published during the preceding year.
Published Scientific Papers of the National Institutes of Health
Each issue lists papers published during the preceding year.
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Drug Studies in the Elderly
Clinical trials are the most definitive tool for evaluation of the applica bility of clinical investigations. The main objective of clinical investiga tions is to assess the potential value of a therapeutic entity in the treat ment or prophylaxis of a disease or a condition. It is also deemed necessary at this stage to obtain information regarding the undesirable side effects, associated risks, and their interrelationship with clinical assessments. Most of these clinical investigations conform, in some form or fashion, to the guidelines adopted by the Food and Drug Administration (FDA) for a given class of compounds. Clinical investigations in the past have not included specific studies in special or subpopulations, e.g., the elderly. Because of an ever-increasing elderly population, newer policies for clinical investigations are now being debated with the recognition of enhanced drug sensitivity in this special population. This key research activity can lead not only to improved health care in the elderly but also to control of its costs.
