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Novel Apoptotic Regulators in Carcinogenesis
Our recent understanding of the cellular and molecular defects and the regulation of the apoptotic signalling pathways has resulted in rationally designed anticancer strategies and the development of novel agents that regulates apoptosis. A comprehensive review of all apoptotic-related anticancer therapies is not the purpose of this book. However, in the volume of this book with 11 chapters, we have described a number of novel apoptotic regulators that have shown promising value and also great feasibility for cancer treatment. These novel agents either occur naturally or are chemically synthesized. While we are excited about the discovery and development of these novel apoptotic regulators a...
Patterning and Cell Type Specification in the Developing CNS and PNS
The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development ...
Bioactive Compounds and Cancer
Because of the wealth of new information generated by the scientific community during the last decade on the role of nutrition on cancer risk, this book provides a forum for presentation and discussion of recent scientific data and highlights a set of dietary recommendations. Bioactive Compounds and Cancer presents chapters that highlight laboratory and clinical findings on how selected nutrients function as signaling molecules and, as such, influence cellular behavior and cancer predisposition. This important compendium focuses on understanding the role of nutrition in cancer biology, the molecular action of bioactive food components and xenobiotics on cancer risk, the role of dietary components in cancer prevention and/or treatment, and nutrition education with the most up to date dietary recommendations that may reduce cancer risk. This volume will be of interest to specialized health professionals, clinicians, nurses, basic and clinical researchers, graduate students, and health officials of public and private organizations.
Lipids
For the 6th Edition of this highly regarded textbook devoted to lipids, the title has been modified from Lipid Biochemistry to Lipids to acknowledge the coming together of biological and medical sciences, the increasingly blurred boundaries between them and the growing importance of lipids in diverse aspects of science and technology. The principal aims of this new edition - to inform students and researchers about lipids, to assist teachers and encourage further research – have not changed since previous editions. Significant advances in lipid science have demanded yet another extensive rewriting for this edition, with the addition of two new authors, to cover new knowledge of genes codin...
Fish and Fish Oil in Health and Disease Prevention
Fish and Fish Oil in Health and Disease Prevention provides an authoritative review of the role of fish and fish oil intake in the promotion of human health. This up-to-date volume provides a complete examination of intake patterns as well as research evidence of intake in disease prevention and treatment. Readers will gain knowledge ranging from the current state of fish and fish oil intake, their health promoting effects and influences on individual response, how they influence development and health maintenance through the life cycle, and their role in disease prevention and treatment. This book is an invaluable resource for all researchers working to understand the relationship between f...
C come camorra
Per non togliere al lettore il gusto della scoperta, mi limito a anticipare che queste pagine cominciano con un omicidio di mafia e proseguono raccontando i tentativi di un’insegnante sveglia e appassionata di trarne spunto per risvegliare l’attenzione degli alunni sulla camorra e, più in generale, sulle organizzazioni criminali…Con tutte le difficoltà del caso, perché in certi territori la presenza mafiosa è così asfissiante da generare meccanismi di chiusura e di rimozione, oppure può capitare che un insegnante trovi nella sua classe ragazzini che appartengono a famiglie di mafia, abituati sin da piccoli a respirare un certo sistema di “valori” e a ritenere normale ciò che normale non è. Ancora una volta la chiave sta nel saper declinare la cosiddetta “educazione alla legalità” in una più ampia e profonda educazione alla responsabilità… E se è vero che una democrazia cresce solo attraverso coscienze inquiete e alla ricerca, questi insegnanti sono anche i primi contribuenti di un PIL importante quanto trascurato: quello che misura la dignità e la libertà di ciascuno di noi. don Luigi Ciotti
