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Translational Research in Breast Cancer
This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer.
Rookie Directors: NOH Dong-seok, KIM Tai-sik, CHO Chang-ho, KIM Dong-hyun, MIN Boung-hun
v. 1 written by Jang Byung-won, Choi Eun-young; translated by Shin Mi-kyung and -- v. 2 written by Lee Sang-yong, Kwon Eunsun; translated by Colin A. Mouat.
Screening and Risk Reduction Strategies for Breast Cancer
This book provides readers with the most up-to-date practical information on breast cancer screening. Since breast cancers are highly heterogeneous, time to clinical onset from the initial carcinogenesis differs diversely between cancers. Pathological germline variants and driver mutations cause a high lifetime risk of breast cancer. The lifetime risks are various according to what genes are pathologically dysfunctional. Integrated omics and imaging technologies have established varying tumour characteristics. Thus, this book suggests that a more individualised scheme is required to improve breast cancer screening. A key aim is to demonstrate how multiple diagnostic imaging modalities such a...
Personalized Treatment of Breast Cancer
This book deals with the essential factors in the personalization of treatment for primary breast cancer. These include host issues, lymph node surgery, radiation therapy, and preoperative systemic treatment requiring specialized knowledge, multidisciplinary care experience, techniques, and research. Locoregional treatment in conjunction with systemic treatments is another important factor, with options for local therapy significantly affected by genetic BRCA mutation. Axillary treatment issues have become top priorities in recent primary breast cancer care, and these are highlighted in the book’s presentation of technological advances in lymph node mapping and diagnosis, axillary clearanc...
Color Atlas of Thyroid Surgery
This color atlas is a detailed guide on how to perform open, endoscopic, and robotic thyroidectomy techniques safely and effectively. Each chapter offers step-by-step descriptions of essential surgical procedures and techniques. Relevant information is included on surgical anatomy, and clear guidance is provided on preoperative set-up, draping, instrumentation, and complications and their treatment. The description of endoscopic thyroidectomy techniques focuses on the bilateral axillo-breast approach (BABA), while in the case of robotic thyroidectomy both BABA and the bilateral axillo-postauricular approach are described. In each case, the evidence supporting the technique is carefully examined. In the closing chapter, the role of new energy sources in thyroid surgery is discussed. The lucid text is supported by more than 200 full-color illustrations clarifying surgical anatomy, instrumentation, and procedures, and surgical video clips are also available to readers via a website. This atlas will be invaluable in enabling surgeons to achieve optimal outcomes when performing thyroid surgery.
GUYnecology
For more than a century, the medical profession has made enormous efforts to understand and treat women’s reproductive bodies. But only recently have researchers begun to ask basic questions about how men’s health matters for reproductive outcomes, from miscarriage to childhood illness. What explains this gap in knowledge, and what are its consequences? Rene Almeling examines the production, circulation, and reception of biomedical knowledge about men’s reproductive health. From a failed nineteenth-century effort to launch a medical specialty called andrology to the contemporary science of paternal effects, there has been a lack of attention to the importance of men’s age, health, and exposures. Analyzing historical documents, media messages, and qualitative interviews, GUYnecology demonstrates how this non-knowledge shapes reproductive politics today.
Computational Science - ICCS 2007
Part of a four-volume set, this book constitutes the refereed proceedings of the 7th International Conference on Computational Science, ICCS 2007, held in Beijing, China in May 2007. The papers cover a large volume of topics in computational science and related areas, from multiscale physics to wireless networks, and from graph theory to tools for program development.
Dietary Pattern and Health
This book is a printed edition of the Special Issue "Dietary Pattern and Health" that was published in Nutrients
