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Epigenetics and Cancer
Overall, this book illustrates the complexities of the regulation and deregulation of genes mediated through epigenetics in the development and progression of human malignancies. All the articles have been carefully chosen to represent several cancer systems with state of our knowledge on the role of epigenetic deregulation of microRNAs (miRNAs) and their target mRNAs along with epigenetic deregulation of mRNAs. This book also illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in modulating the epigenetic reprogramming of miRNAs and mRNAs for the prevention and/or treatment of human malignancies. It is well known that genetic aberrations, esp...
Genotoxicity and Mutagenicity
This edited book, "Genotoxicity and Mutagenicity - Mechanisms and Test Methods", aims to present the latest developments from different fields, highlighting the detrimental influence that mutagenic and genotoxic agents inflict on DNA and how antimutagenic and anticarcinogenic modulators are able to reduce the negative impact of such toxic agents on living species.
Tumor Microenvironment and Cancer Therapy
It is well established that the tumor microenvironment(TME) plays a pivotal role in tumor initiation, progression and therapeutic resistance by creating a dynamic interaction with cancer cells. TME is comprised of extracellular matrix (ECM), growth factors, nutrients, blood and lymphatic vessels, and non-cancer stromal cells, which serve as a sustained niche for cancer cells to proliferate and metastasize. Notably, various cellular components in TME, including endothelial cells, fibroblasts, pericytes, adipocytes, immune cells, cancer stem cells, and vasculature, could promote tumor’s immune evasion and growth.
AACR 2016: Abstracts 1-2696
The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 1-2696 presented on April 17-18, 2016, at the AACR Annual Meeting.
A School in Ren Village
By adopting oral history and fieldwork methods and exploring historical data, this book chronologically depicts the development of the schools and education in a village in North China over a century. The book reveals how education and school life in the rural village are being impacted not only by its own history and traditions, but also by external powers; more specifically, the development of rural schools is influenced by the tensions between Chinese and Western culture, between history and reality, between countryside and cities, and between national and local powers. In essence, villagers’ educational experience is actually a battlefield for school education and local tradition – t...
AACR 2016: Abstracts 2697-5293
The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 2697-5293 presented on April 19-20, 2016, at the AACR Annual Meeting.
China’s Provinces and Populations
This manual provides an overview of China's administrative geography, history, and populations of all 31 provinces, as well as Hong Kong, Macao and Taiwan. It focuses primarily on how the provinces came to be, how they were named, as well as their people and populations throughout history. In addition to extensive use of bilingual names (Chinese-English) for specificity, this resource is unique in the datasets contained therein: (1) Up-to-date residential populations of mainland China using the latest decennial (2020) census, and (2) political-administrative registered household (hukou) data based on official numbers provided by People’s Republic of China (PRC) Ministry of Public Security ...
Therapeutic Relevance and Mechanisms of Neuro-Immune Communication in Brain Injury
The brain is a critical organ with neuro-immune communication. The nervous system and immune system evolved to provide regulation of physiological homeostasis and protect against threats. Neuro-immune communication is correlated with physiological functions of various tissues and organs, and the internal environment balance. In brain trauma, the neural network is destroyed and the neuro-immune communication process is impaired. However, the research on this process is insufficient and limited. A thorough clarification of the cellular and molecular mechanisms of neuro-immune communication in brain injury is an essential necessary endeavor in the search for new therapeutic targets for brain injury. This Research Topic is devoted to the cellular and molecular mechanisms of neuro-immune communication in brain injury and on the meaningful exploration of how the nervous system regulates the immune system to promote neurofunctional recovery after brain injury.
