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In its extensively revised and updated Second Edition, this book provides a solid foundation for readers interested in clinical research. Discussion encompasses genetic, pharmacoepidemiologic and implementation research. All chapters have been updated with new information and many new tables have been added to elucidate key points. The book now offers discussion on how to handle missing data when analyzing results, and coverage of Adaptive Designs and Effectiveness Designs and new sections on Comparative Effectiveness Research and Pragmatic Trials. Chapter 6 includes new material on Phase 0 Trials, expanded coverage of Futility Trials, a discussion of Medical Device approval, Off Label Drug ...
The year is 1748. Elewa, known as ‘the Daughter of Peace’, bears a heavy responsibility on her young shoulders: to maintain the fragile truce between the warring peoples of her West African kingdom. But as she begins to understand her role in the peace negotiations, even greater pressures emerge. Elewa discovers that she has Yeseni, a powerful gift that allows her to see events from any point in time, and to travel into the past and future. When she experiences horrific visions of life aboard a slave ship, she realises she has to face the ultimate crossroads. She could use her gift to intervene in the past and try to prevent the transatlantic slave trade ever taking place. But that means she, as the Daughter of Peace, would be leaving her village behind at a precarious moment in the reconciliation process. Whichever path she chooses to take, the future of her people lies on her shoulders.
This book raises questions and provides a starting point for health practitioners ready to reorient public health practice to address the root causes of health inequities.
Now in its thoroughly updated Third Edition, the Hypertension Primer is a comprehensive, readable source of state-of-the-art scientific and clinical information on hypertension. The book contains more than 150 short chapters by distinguished experts that cover every aspect of hypertension and its pathogenesis, epidemiology, impact, and management. The chapters are grouped into three well-organized sections--basic science, population science, and clinical management--and each chapter is cross-referenced to other relevant chapters. Each chapter is easily digestible and begins with a bulleted list of key points.
This volume is a serious attempt to open up the subject of European philosophy of science to real thought, and provide the structural basis for the interdisciplinary development of its specialist fields, but also to provoke reflection on the idea of ‘European philosophy of science’. This efforts should foster a contemporaneous reflection on what might be meant by philosophy of science in Europe and European philosophy of science, and how in fact awareness of it could assist philosophers interpret and motivate their research through a stronger collective identity. The overarching aim is to set the background for a collaborative project organising, systematising, and ultimately forging an identity for, European philosophy of science by creating research structures and developing research networks across Europe to promote its development.
Unequal Health asks why some individuals are living longer and enjoying better health than others. By considering popular beliefs about the relevance of such factors as sex, race, poverty, and health habits, Grace Budrys moves beyond factors that receive a great deal of media attention-such as smoking, diet, exercise, and even genetic inheritance-and examines those factors that are far more difficult to identify and track, such as relative income and relative social status.
Provides a seven-day vitality plan, complete with menus, exercise guidelines, and lifestyle solutions, that will help women feel and look younger in just one week.
For many years, laboratory dogs have served as important animal models for biomedical research that has advanced human health. Conducted at the request of the U.S. Department of Veterans Affairs (VA), this report assesses whether laboratory dogs are or will continue to be necessary for biomedical research related to the VA's mission. The report concludes that using laboratory dogs in research at the VA is scientifically necessary for only a few areas of current biomedical research. The report recommends that the VA adopt an expanded set of criteria for determining when it is scientifically necessary to use laboratory dogs in VA biomedical research; that the VA promote the development and use of alternatives to laboratory dogs; and highlights opportunities for the VA to enhance the welfare of laboratory dogs that are being used in biomedical research areas for which they have been deemed necessary.