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Synthetic biology encompasses a variety of different approaches, methodologies and disciplines, and many different definitions exist. This Volume of Methods in Enzymology has been split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation. - Encompasses a variety of different approaches, methodologies and disciplines - Split into 2 parts and covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation
Synthetic biology encompasses a variety of different approaches, methodologies and disciplines and many different definitions exist. This volume covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation.
Learn the basics—and more—of nanoscale computation and communication in this emerging and interdisciplinary field The field of nanoscale computation and communications systems is a thriving and interdisciplinary research area which has made enormous strides in recent years. A working knowledge of nanonetworks, their conceptual foundations, and their applications is an essential tool for the next generation of scientists and network engineers. Nanonetworks: The Future of Communication and Computation offers a thorough, accessible overview of this subject rooted in extensive research and teaching experience. Offering a concise and intelligible introduction to the key paradigms of nanoscale...
Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.
The demands of increasingly complex embedded systems and associated performance computations have resulted in the development of heterogeneous computing architectures that often integrate several types of processors, analog and digital electronic components, and mechanical and optical components—all on a single chip. As a result, now the most prominent challenge for the design automation community is to efficiently plan for such heterogeneity and to fully exploit its capabilities. A compilation of work from internationally renowned authors, Model-Based Design for Embedded Systems elaborates on related practices and addresses the main facets of heterogeneous model-based design for embedded ...
This book arises from experience the authors have gained from years of work as industry practitioners in the field of Electronic System Level design (ESL). At the heart of all things related to Electronic Design Automation (EDA), the core issue is one of models: what are the models used for, what should the models contain, and how should they be written and distributed. Issues such as interoperability and tool transportability become central factors that may decide which ones are successful and those that cannot get sufficient traction in the industry to survive. Through a set of real examples taken from recent industry experience, this book will distill the state of the art in terms of System-Level Design models and provide practical guidance to readers that can be put into use. This book is an invaluable tool that will aid readers in their own designs, reduce risk in development projects, expand the scope of design projects, and improve developmental processes and project planning.
Platform Based Design at the Electronic System Level presents a multi-faceted view of the challenges facing the electronic industry in the development and integration of complex heterogeneous systems, including both hardware and software components. It analyses and proposes solutions related to the provision of integration platforms by System on Chip and Integrated Platform providers in light of the needs and requirements expressed by the system companies: they are the users of such platforms, which they apply to develop their next-generation products. This is the first book to examine ESL from perspectives of system developer, platform provider and Electronic Design Automation.
The main objective of this book is to understand and manipulate the physical, chemical, and biological processes that occur in microscale fluidic systems. It explains microfluidics and biofluidics and their application to innovative design and computational intelligence methods used for solving nonlinear problems of engineering. It also covers new evolving trends in engineering related to green technologies, biomedical devices, computer-aided design, smart manufacturing, artificial intelligence systems, and sustainability. The book adopts a balanced approach between academic research and industrial applications. Features: Includes design and fabrication of microfluidic devices and systems for biological and medical applications. Investigates physical properties and behavior of fluids at the microscale level. Covers the development of microfluidic sensors and actuators for medical and environmental monitoring. Studies fluid dynamics in biological systems. Reviews tribological analysis of microfluidic and biofluidic devices for medical applications. This book is aimed at researchers and graduate students in fluid dynamics, mechanical engineering, and bioengineering.
This book constitutes the refereed proceedings of the International Symposium on Bioinformatics Research and Applications, ISBRA 2012, held in Dallas, Texas, USA, in May 2012. The 26 revised full papers presented together with five invited talks were carefully reviewed and selected from 66 submissions. The papers address issues on various aspects of bioinformatics and computational biology and their applications.