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Each year pharmaceutical companies invest billions of dollars in clinical trials of drugs used for the treatment of central nervous system diseases. Due to enormous progress in basic pharmaceutical research in recent years, controlled tests of new medications are flourishing and these trials have rapidly become an intense focus of practical medical research. Aware of the complexities presented in the design, execution, and evaluation of clinical trials, Marc Hertzman and Douglas E. Feltner bring together a collection of essays that dissect the scientific, psychosocial, political, and ethical concerns that must be examined for any CNS trial. The internationally known contributors examine conc...
Presents the complicated process of CNS drug development in a way that is engaging and informative for professionals and students.
Groundbreaking study of the history and ethics of addiction science
Why the race to apply AI in psychiatry is so dangerous, and how to understand the new tech-driven psychiatric paradigm. AI psychiatrists promise to detect mental disorders with superhuman accuracy, provide affordable therapy for those who can’t afford or can’t access treatment, and even invent new psychiatric drugs. But the hype obscures an unnerving reality. In The Silicon Shrink, Daniel Oberhaus tells the inside story of how the quest to use AI in psychiatry has created the conditions to turn the world into an asylum. Most of these systems, he writes, have vanishingly little evidence that they improve patient outcomes, but the risks they pose have less to do with technological shortcom...
Therapeutic Jurisprudence (TJ) is a way of exploring the ways in which the law in practice (as opposed to theory) can exert positive or negative effects on real people in actual situations. This book applies the inquiries of TJ to the areas of geriatrics and gerontology, focusing on facets of laws pertaining specifically to older persons in the United States. Through a series of thoroughly referenced chapters, mixing analytic discussion and case examples, Kapp asks such questions as: Is legal involvement and intervention in the lives of older persons a good thing for both the intended beneficiaries and society as a whole? What is therapeutic jurisprudence and why is it relevant to older Amer...
Includes data for the Ann Arbor, Dearborn, and Flint campuses.
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Each chapter provides excerpts from statutes and regulations, judicial opinions, literature, commentary, case examples, and suggested resources.
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Translational Medicine in CNS Drug Development, Volume 29, is the first book of its kind to offer a comprehensive overview of the latest developments in translational medicine and biomarker techniques. With extensive coverage on all aspects of biomarkers and personalized medicine, and numerous chapters devoted to the best strategies for developing drugs that target specific disorders, this book presents an essential reference for researchers in neuroscience and pharmacology who need the most up-to-date techniques for the successful development of drugs to treat central nervous system disorders. Despite increases in the number of individuals suffering from CNS-related disorders, the developme...