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Everything to Know About GENE: Etymology, Definition, History, Function and much more. A Concise Pedagogy of GENE.
Everything to Know About GENE: Etymology, Definition, History, Function and much more. A Concise Pedagogy of GENE. We all know about genetics, how they are made up of DNA. Many young people will have had their first information about genetics and DNA from the legendary film Jurassic Park, which spoke about DNA and genetics in making dinosaurs. However, humans have DNA too, and for us, it can influence everything about us. Everyone has DNA, and therefore everyone has genes. Genes are the basic physical and functional units of heredity, they are made up of DNA, and one gets them from his parents. How we understand genes is often molded by what we know in popular culture, unless you are a sc...
Everything Need to Know About “Hair Shaft Structure” & “Hair Shaft Disorders”
Everything Need to Know About “Hair Shaft Structure” &“Hair Shaft Disorders” Hair shaft disorders are a diverse group of congenital and acquired abnormalities of the hair shaft. Some hair shaft disorders cause fragility of the hair shaft leading to increased hair breakage; others lack fragility but alter the appearance or texture of the hair. Hair shaft disorders can occur independently or in association with genetic or acquired diseases. An attempt has been made in this E-Booklet to introduce the Structure of Hair Shaft, prior to reviewing the causes, features, and probable treatment of various hair shaft disorders along with plenty of ILLUSTRATIONS for better understanding. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)
A Compendium of "Pseudo" codification in Dermatology.
A Compendium of "Pseudo" codification in Dermatology. Part -I Welcome to this E-Booklet, an exploration of "Pseudo" Codification in Dermatology.. This e-book is designed to provide Medicos with a comprehensive understanding of “Pseudo" codification in Dermatology., divided into three distinct parts: Part-I, Part-II, & Part-III, for a structured and in-depth learning experience. The word ‘pseudo’ means ‘Unreal’, ‘False’ or ‘Fake’, and it has deep roots in dermatology providing Herculean task to differentiate and understand the real conditions/diseases/signs in dermatology. A total of 52 pseudo-terms have been compiled so far in reference to dermatology. Most of these pseudo-...
Exploring Transmission, Pathogenicity related Mechanisms, Biomolecular study and Worldwide Societal Impact of Covid-19.
Exploring Transmission, Pathogenicity related Mechanisms, Biomolecular study and Worldwide Societal Impact of Covid-19. The viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or novel coronavirus or COVID-19 (CoV-19) is known as a pandemic. After SARS-CoV and Middle East respiratory syndrome (MERS)–related CoV, COVID-19 is the third most pathogenic virus, hazardous to humans which have raised worries concerning the capacity of current security measures and the human services framework to deal with such danger. Recently according to WHO, the mortality rate of COVID-19 exceeded that of SARS and MERS in view of which COVID-19 was declared as public health eme...
10 Erythematous Conditions: Need to know Types, Causes, Symptoms and Treatments. Part -1. & Part -2.
10 Erythematous Conditions: Need to know Types, Causes, Symptoms and Treatments. Erythema is a broad category of skin condition that can impact any area of the skin and mucous membranes. It usually occurs in response to disease or infection in reaction to a drug. Severity of the rash ranges from mild to life threatening. Erythema is an abnormal redness of skin or mucous membranes. Capillary congestion causes the condition, and red splotches on the hands or feet are classic examples of it. Although it most commonly presents on the skin and mucous membranes, erythematous lesions can appear on all parts of the body in various patterns and colours. A variety of factors, including skin tone and b...
Differences/Similarities Between Epistatic Gene and Hypostatic Gene. A Concise Overview.
Differences/Similarities Between Epistatic Gene and Hypostatic Gene. A Concise Overview. Epistasis occurs if the effect of one variant affecting a complex trait depends on the genotype of a second variant affecting the trait. For example, consider two loci (A, B), each with two alleles (A1, A2, B1, B2). Epistasis would occur, for example, if the A2A2B2B2 genotype had a high disease risk, but the eight other possible two-locus genotypes had no effect on risk. This is only one of many possible forms of epistatic interactions between two loci. Epistasis is one of several non-mutually exclusive explanations for small effects, missing heritability and lack of replication of top trait-associate...
What is Transthyretin Amyloid Cardiomyopathy (ATTR-CM)?
What is Transthyretin Amyloid Cardiomyopathy (ATTR-CM)? Transthyretin amyloid cardiomyopathy (ATTR-CM) is one of the types of systemic amyloidosis in which misfolded transthyretin (TTR) protein gets deposited in the myocardium Transthyretin amyloid cardiomyopathy is a quaint but severe cause of restrictive cardiomyopathy, caused by the accumulation of transthyretin fibrils in the myocardium. It can present with new or worsening heart failure or new conduction system disease. Due to the lack of knowledge and efficient diagnostic modalities, this disease was often missed in clinical settings. However, with the advent of contemporary cardiac imaging techniques and effective therapeutic options, early diagnosis and treatment are possible. It is strived in this Booklet to review the pathophysiology, diagnosis, and treatment of Transthyretin amyloid cardiomyopathy and highlights the role of the interprofessional team along with plenty of ILLUSTRATIONS for better understanding. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)
Dysgraphia: Symptoms, Causes, Diagnosis, Treatment, Management etc. A Concise Review.
Dysgraphia: Symptoms, Causes, Diagnosis, Treatment, Management etc. A Concise Review. In the past, the term 'dysgraphia' was used to refer to both motor coordination difficulties affecting writing, as well as persistent difficulty expressing thoughts in writing due to weaknesses in literacy and/or language conventions (such as spelling, grammar and punctuation). To avoid any confusion between the two, a distinction has more recently been made with a specific learning disorder in written expression (Dysgraphia) referring to: a. Language-based difficulties involved in constructing meaningful and effectively structured expressive writing and b. Ongoing weaknesses in spelling and punctuation tha...
What is “Cytokine Storm”? Understanding its Role in the Pathology of Clinical & Infectious Disease at Molecular Level.
What is “Cytokine Storm”? Understanding its Role in the Pathology of Clinical & Infectious Disease at Molecular Level. The term “Cytokine Storm” was popularized largely in the context of avian H5N1 influenza virus infection, bringing the term into popular media. The cytokine storm has captured the attention of the public and the scientific community alike, and while the general notion of an excessive or uncontrolled release of proinflammatory cytokines is well known, the concept of a cytokine storm and the biological consequences of cytokine overproduction are not clearly defined. Cytokine storms are associated with a wide variety of infectious and noninfectious diseases. In this E-B...
What is “Exploding Head Syndrome”? Here's What to Know ...
What is “Exploding Head Syndrome”? Here's What to Know ... Exploding head syndrome (EHS) is a rarely reported disorder of unknown etiology characterized by a momentary loud noise that patients usually experience during the early stages of sleep. Fear, terror, palpitations, or a forceful heartbeat usually follow with occasional descriptions of an associated flash of light or a sensation of stopping breathing. EHS can occur at any age, especially in people older than 50 years. Diagnosis is made by the clinical history and testing is not required. Although explanation and reassurance suffice for most, there are anecdotal reports of benefits for treatment with and use of an oral appliance for a patient with obstructive sleep aponea. An effort has been made in this Booklet to describe Etiology, Epidemiology, Clinical presentation, Evaluation, Management etc. of Exploding Head Syndrome and explain the role of health care teams in managing patients with this condition. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)
