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Mathematical Models and Methods for Living Systems
The aim of these lecture notes is to give an introduction to several mathematical models and methods that can be used to describe the behaviour of living systems. This emerging field of application intrinsically requires the handling of phenomena occurring at different spatial scales and hence the use of multiscale methods.Modelling and simulating the mechanisms that cells use to move, self-organise and develop in tissues is not only fundamental to an understanding of embryonic development, but is also relevant in tissue engineering and in other environmental and industrial processes involving the growth and homeostasis of biological systems. Growth and organization processes are also important in many tissue degeneration and regeneration processes, such as tumour growth, tissue vascularization, heart and muscle functionality, and cardio-vascular diseases.
Modeling in Ecology and Epidemiology
Nature is filled with biotic organisms (bacteria, insects, plants, animals, etc.) and B-biotic elements of the environment (air, soil, and water). The life cycle of biotic elements is entirely dependent on the abiotic elements. Pathogens like viruses, bacteria, or other infectious agents can cause diseases in living creatures. The pathogens are capable of causing infectious disease directly, or they can also spread through the other multiple species (known as the Vector). Zoonosis is an infectious disease that has jumped from non-human animals to humans. Zoonotic pathogens may be bacterial, viral, or parasitic, involve unconventional agents, and can spread to humans through direct contact with food, water, or the environment. Currently, highly infectious human populations of diseases include HIV, SARS-CoV-2 (Covid-19), H1N1 flu (swine flu), Dengue (Vector-borne), and so forth. Another essential feature is the pollutant of the environment (like the pesticide used for agricultural purposes and oil in the seawater) that spread among the animals through the food. Therefore, it is crucial to study infectious disease dynamics in ecological systems and human populations.
Strength in Numbers: The Rising of Academic Statistics Departments in the U. S.
Statistical science as organized in formal academic departments is relatively new. With a few exceptions, most Statistics and Biostatistics departments have been created within the past 60 years. This book consists of a set of memoirs, one for each department in the U.S. created by the mid-1960s. The memoirs describe key aspects of the department’s history -- its founding, its growth, key people in its development, success stories (such as major research accomplishments) and the occasional failure story, PhD graduates who have had a significant impact, its impact on statistical education, and a summary of where the department stands today and its vision for the future. Read here all about how departments such as at Berkeley, Chicago, Harvard, and Stanford started and how they got to where they are today. The book should also be of interests to scholars in the field of disciplinary history.
Mathematical and Computational Oncology
This book constitutes the refereed proceedings of the Third International Symposium on Mathematical and Computational Oncology, ISMCO 2021, held in October 2021. Due to COVID-19 pandemic the conference was held virtually. The 3 full papers and 4 short papers presented were carefully reviewed and selected from 20 submissions. The papers are organized in topical sections named: statistical and machine learning methods for cancer research; mathematical modeling for cancer research; spatio-temporal tumor modeling and simulation; general cancer computational biology; mathematical modeling for cancer research; computational methods for anticancer drug development.
Cell Movement
This book contains a collection of original research articles and review articles that describe novel mathematical modeling techniques and the application of those techniques to models of cell motility in a variety of contexts. The aim is to highlight some of the recent mathematical work geared at understanding the coordination of intracellular processes involved in the movement of cells. This collection will benefit researchers interested in cell motility as well graduate students taking a topics course in this area.
Managing Complexity, Reducing Perplexity
”Managing Complexity, Reducing Perplexity” is devoted to an overview of the status of the art in the study of complex systems, with particular focus on the analysis of systems pertaining to living matter. Both senior scientists and young researchers from diverse and prestigious institutions with a deliberately interdisciplinary cut were invited, in order to compare approaches and problems from different disciplines. The common aim of the contributions was to analyze the complexity of living systems by means of new mathematical paradigms that are more adherent to reality and which are able to generate both exploratory and predictive models that are capable of achieving a deeper insight into life science phenomena.
Justified Modeling Frameworks and Novel Interpretations of Ecological and Epidemiological Systems
The Lotka-Volterra and the Kermack-McKendrick models are well celebrated and widely recognized in the field of ecology and epidemiology. Several modified ordinary differential equation models have been proposed over the last many decades to rationalize complex biological phenomena. In the current century, researchers have paid much attention to developing new modeling frameworks with delay differential equations, difference equations, fractional order systems, stochastic differential equations, etc. No doubt, these models have emerged many new bifurcations theory and methods which have equally contributed to the advances of Mathematics and interdisciplinary research. It is argued that these ...
Analysis of Reaction-Diffusion Models with the Taxis Mechanism
This open access book deals with a rich variety of taxis-type cross-diffusive equations. Particularly, it intends to show the key role played by quasi-energy inequality in the derivation of some necessary a priori estimates. This book addresses applied mathematics and all researchers interested in mathematical development of reaction-diffusion theory and its application and can be a basis for a graduate course in applied mathematics.
