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Art Management
In the 21st century, there is an enormous need for a basic knowledge of management in the cultural sector. This publication fills the gap between general management theory and cultural praxis. It offers information on the global dimension of art management, digitization of culture, strategy formation in the cultural sector, the structure of a cultural organization, cultural leadership. Casestudies are presented from different parts of the world, rooted in local resources but from a global perspective.
Immunology of Ocular Tumors
The eye and the ocular adnexa may give rise to over three hundred histologically different tumors - by far the largest tumor variety of the human body. However, the immunological behavior of these tumors has only been explored in some cases, although it is well established that the eye is an immune-privileged site in which cells that express foreign antigens escape immune-mediated elimination. Human tumors also create an immune-privileged surrounding and thereby escape from anti-tumor immune responses. Highlighting aspects of ocular and general tumor, this text summarizes the role of the immune system and how tumor tissue can influence various parameters (T-cells, NK-cells, HLA-expression, apoptosis), leading to escape mechanisms used by the tumor. New therapeutic regimens urgently required by patients are also reviewed, and the immunological behavior of skin melanoma is compared to choroidal melanoma, whilst basal cell carcinoma of the ocular lid is compared to those of the skin.
Advances in Immunology
Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
Palaeohistoria 53/54 (2011/2012)
The annual journal Palaeohistoria is edited by the staff of the Groningen Institute of Archaeology, and carries detailed articles on material culture, analysis of radiocarbon data and the results of excavations, surveys and coring campaigns.
Cytokines in Hemopoiesis, Oncology, and AIDS
The clinical and experimental effects of cytokines have been realized for a long time. The clinical effects of tumor necrosis factor were noted almost 100 years ago. The basic biological effects of interferons and the hemopoietic growth factors have been known for more than 20 years. Given the basis of modern molecular biotechniques, information concern ing the mediators of cellular interactions is expanding almost exponentially. New principles in the regulation of cell growth, microenvironment, immune response, and malignancy are being discoverd right now. New therapeutic options are becoming available and have, in some areas, already crossed the threshold of clinical application. However, ...
A Bouquet of Archaeozoological Studies
This volume comprises papers presented to Wietske Prummel on the occasion of her retirement from the Groningen Institute of Archaeology (University of Groningen) in 2012. The contributions cover a wide range of topics from all realms of archaeozoology, such as animal husbandry and mobility, bird exploitation and fishery. The papers are dedicated to Wietske in celebration of her scientific career.
The Chaperonins
The first of its kind, this volume presents the latest research findings on the chaperonins, the best studied family of a class of proteins known as molecular chaperones. These findings are changing our view of some fundamental cellular processes involving proteins, especially how proteins fold into their functional conformations. - Origins of the new view of protein folding - Prokaryotic chaperonins - Eukaryotic chaperonins - Evolution of the chaperonins - Refolding of denatured proteins - Organelle biosynthesis - Biomedical aspects
