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Immunofluorescence in Clinical Immunology
Immunofluorescence, a suitable laboratory method for the microscopic demonstration of antigens and antibodies in biological materials, useable, for example, to provide evidence for the pathogenesis of disease in histological or cytological preparations and for tumour cell differentiation. For this reason immunofluorescence has a decisive role as the method of choice for the diagnosis of auto-immune diseases. This primer on immunofluorescence techniques, which first appeared in 1979, is a richly illustrated handbook suitable for everyday practical work in the laboratory, useable as both an introduction to the subject as well as an atlas. In hardly any other area of medicine are there so many new findings to report. The second edition of this book is concerned not only with the detection methods which now form an essential and established part of diagnostic techniques, but also with the most recent research results such as the discovery of antibodies against Auerbach's plexus and against podocytes...
The Autoimmune Diseases
The Autoimmune Diseases is composed of 25 chapters dealing with different aspects of some specific autoimmune diseases. The book begins with the elucidation of the genetic predisposition to autoimmune diseases. Subsequent chapters explore numerous kinds of autoimmune diseases. Other chapters describe the antireceptor antibodies and the sensitivity and specificity of autoantibody testing. This book is designed to provide a deeper understanding of this increasingly important field of medical science for physicians and investigators involved in the diagnosis, treatment, or research of autoimmune diseases.
Stratum Corneum
The stratum corneum is a magnificent example of the successful adaptation of a tissue. Its efficient function is a prerequisite for life itself. We depend on its control of the movement of water through the skin and on its protective role in the prevention of penetration by pathogens or harmful substances. Apart from its functional importance, there is no escaping the fact that the most common skin disorders (psoriasis, eczema, inherited disorders of keratinization, acne) are 'characterised by abnormal keratinization and or scaliness. Despite all this, understanding of its chemistry, structure, physiology and involvement in disease has been sadly deficient; however, there are signs of enligh...
Advances in Immunology
Advances in Immunology
Dermatology in Five Continents
The World Congress of Dermatology (Congressus Mundi Dermatologiae, CMD) is held every 5 years. The purpose of this meeting is to review and summarize the present status of scientific knowledge in clinical dermatology and to in related basic research, to discuss recent results and ideas among colleagues and to contribute to the develop ment of new clinical and scientific research programmes for the future. It is evident that the Proceedings of such a meeting, where major dermatological work from five continents is presented, should be reviewed carefully and published as soon as possi ble. This volume includes the reports of several hundreds of speakers from all over the world as presented during the congress or delivered 6 weeks later. The moving forces behind all this were the International League of Dermatology (ILDS) with its presi dent, Jean Civatte, its general secretary, Nils Thyresson, the members of the Executive Committee (ICD) and the German Organizing Committee with its subcommittee for the scientific programme. In addition, the chairmen of sessions, coordinators, speakers and discussants all contributed to make the 17th CMD in Berlin a full suc cess.
Autoimmune Diseases of the Skin
Autoimmune disorders of the skin remain an enigma for many clinicians and scientists not familiar with these mostly severe and chronic diseases. The book provides an overview and the latest information on the broad spectrum of cutaneous autoimmune disorders for clinicians, scientists and practitioners in dermatology, medicine, rheumatology, ENT, pediatrics and ophthalmology. The book is unique since it presents the state-of-the-art knowledge on pathophysiology, clinical diagnosis and management of these disorders provided by the world experts in the field. The primary intention is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and handle these conditions. The book is illustrated with many tables, illustrative figures and clinical color photographs. The third edition has been thoroughly updated and extended by chapters on paraneoplastic cutaneous syndromes, atopic dermatitis and autoimmunity and Skin manifestations of rheumatic diseases.
