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Oxidative and metabolic diseases represent a large proportion of global challenges to health and quality of life. These diseases are often characterised by the imbalance between the cellular prooxidant (products of metabolic processes) and the antioxidant molecules within the cells. The imbalance often led to the underlying factors that exacerbate the pathogenesis of some life-threatening diseases such as carcinogenesis, obesity, diabetes, and cardiovascular diseases. Natural products, including phytochemicals and functional foods are known for their ability to affect metabolic processes such as ameliorating reactive oxygen species-induced mitochondria dysfunction, mitigating inflammatory response, and other cellular functions that could ameliorate the disease developments. Despite the relatively low toxicities of natural products as compared with synthetic products, further studies are still required to optimize the bioavailability, therapeutics, pharmaceutics, and clinical trials of natural products in patients suffering oxidative and metabolic diseases.
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The term ‘foreign fighters’ describes nationals of one state who – for whatever variety of reasons and motives – travel abroad to take part in a conflict in another state without the promise of financial reward. The majority of attention has so far been focused on the nationals of Western European states who have gone to fight for the so-called Islamic State in Syria. There exist, however, other examples of contemporary European foreign fighters whose travails, motivations and returns have been largely unnoticed and underappreciated. This books attempts to balance this state of affairs by bringing to the fore some lesser known cases of non-terrorist but foreign fighters related to th...
We are very pleased to introduce the Book Version of our Special Issue in Molecules dedicated to the memory of the late Professor Dr. Charles D. Hufford. The issue has been a huge success, with 22 full-length peer-reviewed papers and a tribute by Professor Alice M.Clark. Authors, reviewers, and collaborators from many countries across the worldhave contributed to this endeavour, and we are truly grateful to all. This Special Issue isrepresentative of the broad impact that “Charlie” had on the field of bioactive naturalproducts. This Special Issue comprises papers from Professor Hufford’s former students,colleagues, and collaborators throughout the world who have utilized a wide array o...
To address the growing complexities of childhood cancer, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood has now been separated into two distinct volumes. With this volume devoted strictly to pediatric oncology, and another to pediatric hematology, you will be on the cutting edge of these two fields. This exciting new, full-color reference provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with cancer. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. ...
Although violent extremism is not a new phenomenon, it is increasingly recognized as a major challenge of our times. The recruitment of foreign fighters by extremist organizations, and its potential impact on public safety in the countries from which they come, is also emerging as a complex issue at the forefront of international preoccupations. This book presents the proceedings of the three day NATO Advanced Research Workshop, "Countering Violent Extremism Among Youth to Prevent Terrorism", held in Milan, Italy, in June 2014. The best way to respond to violent extremism in general, and the radicalization of disaffected youth in particular, is far from clear, but the stakes are so high and ...
The Fifth Edition of Greenfield's Surgery has been thoroughly revised, updated, and refocused to conform to changes in surgical education and practice. Reflecting the increasingly clinical emphasis of residency programs, this edition features expanded coverage of clinical material and increased use of clinical algorithms. Key Points open each chapter, and icons in the text indicate where Key Points are fully discussed. Many of the black-and-white images from the previous edition have been replaced by full-color images. This edition has new chapters on quality assessment, surgical education, and surgical processes in the hospital. Coverage of surgical subspecialty areas is more sharply focuse...
The anthology explores the interrelationship between migration and a supposedly existent crisis of the modern nation state. The argument of such a crisis is mainly used by the New Right to stimulate nationalist feelings and provoke hate and aggression. We, in contrast to this perception, argue that from a historical and current perspective, migration is not endangering the nation state, but rather changing the idea of a nation itself by redefining it. In historical as well as current case studies, the authors determine the political dangers of right wing demagogues, while emphasizing the chances, immigration is offering the progress of the nation state. While it will be discussed how nationa...