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El propósito del presente proyecto editorial se enfoca en la profundización teórica y la aplicación práctica de lo urbano-metropolitano, visualizando a este espacio sui generis desde la óptica de múltiples investigaciones científicas, originales e inéditas, las cuales lo explican no sólo desde las diferentes orientaciones disciplinares aplicadas en el locus typicus de cada copartícipe; sino también a partir de la utilización de variadas metodologías operativas, vinculadas a la línea de investigación de cada autor. Dicho sea de paso, todos los capítulos incluidos están firmados por académicos-investigadores de carrera, los cuales cuentan con una amplia y probada experiencia...
This volume provides researchers with protocols that help them investigate known or putative O2 sensing proteins and pathways. The chapters in this book discuss techniques ranging from anaerobic redox midpoint measurement to approaches to control expression of globin genes, which provide detailed methods for researchers interested in expanding their knowledge of O2 sensing systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and comprehensive, Oxygen Sensing: Methods and Protocols is a valuable resource to a wide audience, ranging from microbiologists and cell biologists, to protein biochemists.
Los dieciocho capítulos de este libro permiten identificar seis ejes temáticos los suficientemente sugerentes como para considerarlos como líneas investigativas: el mismo concepto de espacio pública; cómo se imaginan e imponen modelos de ciudades, y hasta qué punto la población enfrenta esas decisiones; hasta qué punto la ciudad es (re)inventada, (re)creada por sus habitantes y sus necesidades de uso y de relacionarse; cómo las personas se relacionan con la ciudad a una escala micro, con los lugares y cómo estos van cenciendo (casi siempre) a los no lugares; la experiencia espacial como tal; y todos aquellos elementos que definen el derecho a la ciudad, entendida ésta como un gran espacio público.
This is not a book on NO biology, nor about hemoglobin, nor about heme-based sensors per se. Of course, it covers all these topics and more, but above all, it aims at providing a truly multidisciplinary perspective of heme-diatomic interactions. The overarching goal is to build bridges among disciplines, to bring about a meeting of minds. The contributors to this book hail from diverse university departments and disciplines – chemistry, biochemistry, molecular biology, microbiology, zoology, physics, medicine and surgery, bringing with them very different views of heme-diatomic interactions. The hope is that the juxtaposition of this diversity will lead to increased exchanges of ideas, app...
Celiac disease is a systemic autoimmune process and appears in genetically predisposed individuals, with a well-known cause, consisting in a permanent intolerance to gluten, a protein contained in the flour of wheat, rye, barley and oats. Worldwide celiac disease affects to 1% of the Caucasian and there is recent evidence that the disease is increasing in USA and Finland among other regions in the world. It is considered to be the most prevalent disease with a genetic predisposition. The clinical forms of presentation are varied. The classical form consisting of diarrhea, anemia and failure to thrive is still common in children, but in the adult patients the symptoms resemble the irritable b...
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The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. Methods in Enzymology is now available online at ScienceDirect — full-text online of volumes 1 onwards. For more information about the Elsevier Book Series on ScienceDirect Program, please visit: http://www.info.sciencedirect.com/bookseries/ This volume is the second of two planned volumes on the topic of globin and other nitric oxide-reactive proteins.
Low-Level Laser Therapy (LLLT) also known as photobiomodulation is almost 50 years old, and recently has been getting increasing acceptance from the scientific, medical, and veterinary communities. Discoveries are constantly being made about the cellular and molecular mechanisms of action, the range of diseases that can be treated is also rising, and home use LED devices are becoming common. This book compiles cutting-edge contributions from the world’s leading experts in Photobiomodulation and LLLT. Chapters cover general concepts, mechanisms of action, in vitro studies, pre-clinical animal studies, veterinary applications and a wide range of clinical topics. Edited by Michael Hamblin from Massachusetts General Hospital and Harvard Medical School, aided by two prominent researchers (Marcelo Sousa and Tanupriya Agrawal), this book will appeal to anyone involved in the basic science, translational aspects and clinical applications of LLLT.