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This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses. It explores current concepts on activity-dependent remodeling of the synaptic cytoskeleton and presents the latest ideas on the different forms of plasticity in synapses and dendrites. Synaptic Plasticity in Health and Disease not only supplies readers with extensive knowledge on the latest developments in research, but also with important information on clinical and applied aspects. Changes in spine synapses in different brain disease states, so-called synaptopathies, are explained and described by experts in the field. By outlining basic research findings as well as physiological and pathophysiological impacts on synaptic plasticity, the book represents an essential state-of-the-art work for scientists in the fields of biochemistry, molecular biology and the neurosciences, as well as for doctors in neurology and psychiatry alike.
This Special Issue of IJMS covers a broad range of cutting-edge aspects related to the organization, function, and role in disease of the actin cytoskeleton. This cellular structure is of fundamental importance for the homeostasis of every eukaryotic cell, from the simplest unicellular organism to the most complex animal cell. The actin cytoskeleton contributes to developing and maintaining cell shape and tissue integrity and is crucial for cell migration, movement of organelles, vesicle trafficking, and the completion of cell division. Elaborate structures like the sarcomere, the inner ear cell stereocilia, and the brush border microvilli are built on actin filament scaffolds. Dozens of act...
The Cultural Politics of Twentieth-Century Spanish Theater argues that twentieth-century artists used the Golden Age Eucharist plays called autos sacramentales to reassess the way politics and the arts interact in the Spanish nation's past and present, and to posit new ideas for future relations between the state and the national culture industry. The book traces the phenomenon of the twentieth-century auto to show how theater practitioners revisited this national genre to manifest different, oftentimes opposing, ideological and aesthetic agendas. It follows the auto from the avant-garde stagings and rewritings of the form in the early twentieth century, to the Francoist productions by the Teatro Nacional de la Falange, to postmodern parodies of the form in the era following Franco's death to demonstrate how twentieth-century Spanish dramatists use the auto in their reassessment of the nation's political and artistic past, and as a way of envisioning its future.
From ca. 1300 a new genre developed in European literature, Neo-Latin drama. Building on medieval drama, vernacular theatre and classical drama, it spread around Europe. It was often used as a means to educate young boys in Latin, in acting and in moral issues. Comedies, tragedies and mixed forms were written. The Societas Jesu employed Latin drama in their education and public relations on a large scale. They had borrowed the concept of this drama from the humanist and Protestant gymnasia, and perfected it to a multi media show. However, the genre does not receive the attention that it deserves. In this volume, a historical overview of this genre is given, as well as analyses of separate plays. Contributors include: Jan Bloemendal, Jean-Frédéric Chevalier, Cora Dietl, Mathieu Ferrand, Howard Norland, Joaquín Pascual Barea, Fidel Rädle, and Raija Sarasti Willenius.
Beauty masks, diapers, wound dressings, wipes, protective clothes and biomedical products: all these high-value and/or large-volume products must be highly compatible with human skin and they should have specific functional properties, such as anti-microbial, anti-inflammatory and anti-oxidant properties. They are currently partially or totally produced using fossil-based sources, with evident issues linked to their end of life, as their waste generates an increasing environmental concern. On the contrary, biopolymers and active biomolecules from biobased sources could be used to produce new materials that are highly compatible with the skin and also biodegradable. The final products can be ...
During the 17th and 18th centuries, as European cultures grappled with the challenges of emergent modernity, ideas about female same-sex relations became a flash-point for contests about authority and liberty, power and difference, desire and duty, mobility and change, order and governance. Exploring a wide range of texts from more than two centuries and multiple language cultures, this book argues for the significance of relations between women to the early modern social imaginary.
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4, 1906 in Tübingen. The celebratory event "Alzheimer 100 Years and Beyond" was organized through the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen. This volume, a collection of articles by the invited speakers and of a few other prominent researchers, is published as a record of those events.
Coppia: aspetti psicologici e terapeutici - Coppia: crisi della coppia - Famiglia: terapie familiari - Psicologia-psicoterapia-psicanalisi-psichiatria: psicoterapia familiare, psicoretapia di coppia.
An anthology of plays from the Spanish Golden Age contains the full text of 15 plays; an introduction to each play with information about the author, the work, performance issues and current criticism; and glossaries with definitions of difficult words and concepts.