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Livestock and its role in the emergence, spread, and evolution of antimicrobial resistance: Animal-to-human or animal-to-environment transmission
The occurrence of multidrug-resistant bacterial pathogens (e.g., Enterobacterales and nonfermenting Gram-negative bacilli) to critically important antimicrobials such as carbapenems and colistin, last-resort antimicrobials, is a global multifactorial problem that involves animal–food–environmental–human sectors, which requires coordinated One Health and Global Health actions. The raising of food-producing animals has been increasing worldwide due to the rapid increase in demand for livestock products driven by human population growth. Consequently, the intensive use of antimicrobials in this sector has been associated with an increase in antimicrobial resistance. In this regard, the concerns associated with animal-to-human or animal-to-environment transmission of bacteria, including zoonotic pathogens, or plasmid-mediated antimicrobial resistance genes have increased in the last decade.
The Pangenome
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, p...
Toxicity Assessment
This book collects protocols from different areas of knowledge to assist in the identification of toxic effects exerted by different xenobiotics. At the same time as classical techniques are presented, modern techniques with alternative models to the use of animals are also presented. Given the ever-increasing exposure to different compounds and their effects on population health, the assessment of multiple endpoints is of utmost importance for better risk assessment, and this collection addresses that need. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Toxicity Assessment: Methods and Protocols aims to serve researchers in this vast field of science as they seek to better understand the mechanisms of action of different xenobiotics.
Pacific Seaweeds
This updated and expanded guide thoroughly documents every aspect of seaweed life, from species identification and seaweed biology to the essential—and often surprising—roles seaweed plays in the marine ecosystem and our everyday lives. Seaweeds are used in everything from cosmetics to sustainable biofuels, and some species, like kelp, contribute to the remediation of coastal ecosystems. Featuring an attractive new full-color design, the expanded Pacific Seaweeds includes updated species descriptions, dozens of additional color photos, new species discovered since the original edition, and brand-new sections on common shore plants and the use of DNA techniques to discover, catalog and identify seaweeds. It also features several new recipes and an essay on umami—because in addition to all its other uses, some species of seaweed make delectable food. Packed with illustrations, vivid color photographs, comprehensive scientific information and further readings, this easy-to-use guidebook will appeal to marine biologists, amateur beachcombers, gourmet foragers and everyone in between.
Multiple Sequence Alignment
Chapter “Alignment of Biological Sequences with Jalview” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Veterans and Agent Orange
From 1962 to 1971, the U.S. military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of U.S. base camps and outlying fire-support bases. In response to concerns and continuing uncertainty about the long-term health effects of the sprayed herbicides on Vietnam veterans, Veterans and Agent Orange provides a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange and other herbicides used in Vietnam. The 2008 report is the eighth volume in this series of biennial updates. It will be of interest to policy makers and physicians in the federal government, veterans and their families, veterans' organizations, researchers, and health professionals.
Cryptology and Network Security
This book constitutes the refereed proceedings of the 20th International Conference on Cryptology and Network Security, CANS 2021, which was held during December 13-15, 2021. The conference was originally planned to take place in Vienna, Austria, and changed to an online event due to the COVID-19 pandemic. The 25 full and 3 short papers presented in these proceedings were carefully reviewed and selected from 85 submissions. They were organized in topical sections as follows: Encryption; signatures; cryptographic schemes and protocols; attacks and counter-measures; and attestation and verification.
Vaccine Delivery Technology
This volume discusses the vaccine development process and the role delivery concepts contribute to a global goal of effective health outcomes. The chapters in this book cover a wide range of topics such as antigen discovery methods; genetic and protein antigen preparation; preparation of viral vaccines as VLPs; viral and non-viral gene delivery; needle-less or non-invasive delivery technology; vaccine storage; and vaccine administration and assessment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics; lists of the necessary materials and reagents; step-by-step, readily reproducible laboratory protocols; and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Vaccine Delivery Technology: Methods and Protocols is a valuable resource for both novice and expert researchers, in and outside the field, who would like to gain insight into the impactful field of vaccines. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
