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The Hypothalamic-Pituitary-Adrenal Axis in Health and Disease
Cushing ́s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.
The Wights
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Activity Anorexia
This volume provides researchers and clinicians with an insight into recent developments in activity anorexia. Much of the basic information on the topic has come from animal literature; the theory of activity anorexia is built on an animal model of self-starvation (rats placed on a single daily feeding run more and more, over days stop eating, and die of starvation). Additionally, experiments that for ethical or practical reasons could not be done with humans may be conducted with other animals. The animal research is extending the understanding of biologically-based reward mechanisms that regulate eating and exercise, environment-behavior interactions that affect anorexia, and the biochemi...
Patient-Reported Outcomes in Endocrine Diseases, An Issue of Endocrinology and Metabolism Clinics of North America, E-Book
In this issue of Endocrinology and Metabolism Clinics, guest editor Eliza B. Geer brings her considerable expertise to the topic of Patient-Reported Outcomes in Endocrine Diseases. - Provides in-depth reviews on the latest updates in Patient-Reported Outcomes in Endocrine Diseases, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
A Case-Based Guide to Clinical Endocrinology
In A Case-Based Guide to Clinical Endocrinology, Second Edition, a renowned group of distinguished clinicians once again provides stimulating instruction and insights into a wide variety of endocrine topics, teaching readers modern management of the conditions described and offering targeted entry into the literature. Importantly, many of the important elements in the current curriculum for clinical endocrine training as recommended by the Association of Program Directors in Clinical Endocrinology, Diabetes and Metabolism are covered in this text. Thoroughly updated, this new edition not only covers new treatment approaches but also emphasizes the latest investigative advances in both imagin...
ACTH Action in the Adrenal Cortex: From Molecular Biology to Pathophysiology
By stimulating adrenal gland and corticosteroid synthesis, the adrenocorticotropic hormone (ACTH) plays a central role in response to stress. In this Research Topic, a particular attention has been given to the recent developments on adrenocortical zonation; the growth-promoting activities of ACTH; the various steps involved in acute and chronic regulation of steroid secretion by ACTH, including the effect of ACTH on circadian rhythms of glucocorticoid secretion. The Research Topic also reviews progress and challenges surrounding the properties of ACTH binding to the MC2 receptor (MC2R), including the importance of melanocortin-2 receptor accessory protein (MRAP) in MC2R expression and funct...
Endocrinology of the Aging Patient, An Issue of Endocrinology and Metabolism Clinics of North America, E-Book
In this issue, guest editors bring their considerable expertise to this important topic. - Contains 12 practice-oriented topics including thyroid and aging; obesity and aging; hypothalamus-pituitary-adrenal axis and aging; male reproduction and aging; osteoporosis and aging; prediabetes and aging; and more. - Provides in-depth clinical reviews on endocrinology of the aging patient, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Diabetes Remission, An Issue of Endocrinology and Metabolism Clinics of North America, E-Book
In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize
Metabolic-associated fatty liver disease, An Issue of Endocrinology and Metabolism Clinics of North America, E-Book
In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Sherouk Fouda and Joseph M. Pappachan bring their considerable expertise to the topic of Metabolic Associated Fatty Liver Disease. Top experts address the various ways metabolic associated fatty liver disease is related to other conditions such as diabetes, sarcopenia, PCOS, and more, as well as the management of MAFLD and cardiovascular implications. - Contains 12 practice-oriented topics including obstructive sleep apnea and MAFLD; the interlink between MAFLD and polycystic ovary syndrome; pregnancy and MAFLD; MAFLD and gut microbiota; and more. - Provides in-depth clinical reviews of metabolic associated fatty liver disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
