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New Concepts of Antiviral Therapy
Antiviral drugs are vital - but imperfect - tools for treatment and prevention of viral infections. Undesirable effects, from drug resistant viruses to low oral bioavailability, toxicity and severe side effects limit clinical usefulness. These factors drive demand for improved antiviral strategies. This book offers an up-to-date review of new drugs and targets, novel modes of action, vector-based treatments and even the blocking of defined genes by inhibiting mRNA formation (siRNA). Includes contributions by acknowledged experts; the book will serve as a compendium for R&D and educational professionals, and be of value for students.
Structure-Function Relationships of Human Pathogenic Viruses
Structure-Function Relationships of Human Pathogenic Viruses provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions. The relation between structural features and the pathogenicity and oncogenicity of some of the most relevant human viral pathogens are demonstrated and the acquisition of defense mechanisms through virus-host interactions are presented. In contrast to textbooks, this volume combines timely research data to provide a holistic view of viral pathogenesis. Furthermore Structure-Function Relationships of Human Pathogenic Viruses illustrates in a single volume the fundamental processes involved in viral life cycles using up-to-date information from research laboratories around the world. Knowledge of these processes is crucial to develop rationales for the design of future drugs. The timeliness of the data and the comprehensive yet concise approach this book takes in order to present the world of viral pathogens should make it a frontrunner in higher education and R&D.
Viral Proteases and Antiviral Protease Inhibitor Therapy
The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets. Viral infections are still difficult to threat and some remained life-threatening diseases in spite of antiviral drug research over decades. Proteases are still regarded as an Achilles’ heel of the pathogens and, thus, protease inhibitors may help to handle the known and the emerging viral threads. The book discusses viral proteases of the most important pathogenic viruses, responsible for severe diseases: AIDS, SARS, Hepatitis, Cytomegalovirus, T-cell lymphotropic virus, Picornavirus. This book focuses specifically on the viral proteas...
Forthcoming Books
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Kürschners deutscher Gelehrten-Kalender
In der 22. Ausgabe von Kürschners Deutschem Gelehrten-Kalender werden rund 70.000 Wissenschaftlerinnen und Wissenschaftler, die an einer deutschsprachigen wissenschaftlichen Institution tätig sind, vorgestellt. Aufgeführt sind die wichtigsten biographischen Daten, Adressen, Angaben zu Forschungsschwerpunkten und Arbeitsgebieten sowie ausführliche bibliographische Hinweise, u.a. mit einer Auswahl der wichtigsten Veröffentlichungen in Zeitschriften, Sammelwerken und Lexika. Im Anhang finden sich ein Nekrolog, ein Fachgebietsregister, ein Festkalender und schließlich eine Liste aller deutschsprachigen Universitäten und Fachhochschulen. Pluspunkte: Die Einträge werden erstellt auf der Grundlage von Selbstauskünften der eingetragenen Personen und sorgfältiger Recherche. Einzigartige Zusammenstellung und Zuverlässigkeit der Daten, gerade im Vergleich mit dem Internet.
Salary Book
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DUZ
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