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Organoid Technology for Disease Modelling and Personalized Treatment
Organoid Technology for Disease Modelling and Personalised Treatment provides a comprehensive overview of current knowledge of the organoid as a human-organ-in-a-dish, a powerful new technology for studying fundamental aspects of human organ development and disease progression in the search for drugs for personalised treatment. This preclinical tool is extensively being utilised as a model for studying human diseases in a dish, which is critical for accurate predictive modelling in precision medicine. The chapters in this book introduces readers to the numerous applications of organoids in various fields of study, as well as ethical considerations associated with organoids. In stem cell biol...
Atoned in Truth
When Lou Brandon retires as the only constable of a small Manitoba town, his life takes on a comfortable but aimless routine. That changes when he slowly becomes friends with the new Catholic priest, Peter Wilson. As the two struggle with life, unlikely circumstances bring them together to investigate a murder long thought solved. Their friendship gives them the space to question the burdens they carry and how these have limited their lives. But examining life, particularly when it has not been lived honestly, is much easier said than done. Learning to face their truths gives them the opportunity to grow, but comes with risks of failure they may be unwilling to face. As Brandon and Wilson draw closer to identifying the real murderer, the uncomfortable relationship between the local Indigenous and non-Indigenous communities threatens to derail their investigation completely. Will they be able to find justice for the victim and reconciliation to themselves before it’s too late?
Crosslinguistic Approaches to Language Analysis
This volume presents cutting edge linguistic research across the fields of syntax, semantics, morphology, translation studies, language acquisition, and phonology. It explores key topics such as bare partitives, differential object marking, the role of clitics, the semantics of grammatical and situational aspect, and existential quantifiers. The data come from English, Greek, Hungarian, Romanian and other Romance languages. Several papers also focus on the issues posed by the translation of various challenging structures into Romanian and other European languages.
Hair Follicle Regeneration
This book aims to comprehensively review the current cell-based strategies under investigation to achieve the regeneration of human hair follicles. The unique capacity of the human hair follicle to self-renew explains why this complex “mini-organ” has always attracted so much interest as a model for researchers to study stem cell biology and regenerative medicine. The hair follicle is considered a main reservoir of cutaneous stem cells, containing several pools of epithelial, melanocyte, and mesenchymal stem cells involved in hair follicle self-regeneration and pigmentation. In addition, while some of the different follicular cell types contribute to hair shaft growth, others participate...
Biomaterials and Tissue Engineering
This contributed volume covers all fundamental principles for researchers and professionals interested in the field of Biomaterials and Tissue Engineering, an interdisciplinary field of research with contributions from biomedical scientists, engineers, and physicians. With a strong focus on biomaterials and scaffolds, the book also covers testing and evaluation pathways for in vitro and in vivo studies. This book also presents a broad range of topics including fundamentals of 3D printing and bioprinting, followed by contemporary technology used in tissue engineering applications as well as currently available biomaterials suitable for tissue repair and regeneration. This volume provides information on: (i) why humans need biomaterials, especially in medical applications, (ii) different types of tissue engineering strategies, and (iii) modeling, characterization, and evaluation of outputs of those strategies. This book is a reference material in the field of tissue engineering, and it is very useful for bachelor, M.Sc., and Ph.D. students, researchers, academics, medical, industry, and healthcare professionals from diverse backgrounds.
