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Nicotinic Acetylcholine Receptors in the Nervous System
The acetylcholine nicotinic receptor is an ionic channel whose aperture is directly controlled by acetylcholine. It is a key molecule in the chemical communication between nerve cells and between nerve cell and muscle. The structure and function of muscular nicotinic receptors have been unraveled in recent years and its beauty and mysteries were reviewed in the Santorini NATO ARW organized by Dr. Maelicke in 1986. The neat, linear structure of this molecule and its conservation throughout evolution, from bacteria to humans, have led to the suggestion that it has reached the optimal structure for performing its function. But when scientists began to look at the nicotinic receptor in the nervo...
Nicotinic Receptors
A comprehensive overview of nicotinic receptors that addresses their history from crystal structure to behavior as well as their implications in disease and potential as therapeutic targets. It includes background information on all subtypes of nicotinic receptors, the most recent information on the distribution throughout the nervous system and discussion of their implications in learning and memory, addiction and neurological and psychiatric disease such as Alzheimer's and Parkinson's. Takes advantage of several recent developments in the fields of optogenetics, viral expression and gene analysis to focus on current knowledge on the functional aspects of nicotinic receptors.
Cholinergic Mechanisms
Providing a cutting-edge profile of research progress in this important field of study, Cholinergic Mechanisms: Function and Dysfunction contains a compilation of the proceedings of the Eleventh ISCM, held in St. Moritz, May 2002. Bringing together 250 contributors from 30 countries, the book presents a comprehensive picture of the cholinergic field. It provides a survey of current understanding of molecular, pharmacological, toxicological, behavioral, and clinical aspects of the cholinergic system. This volume offers a state-of-the-art account of progress in the field from the molecule in the test tube through the cell and the synapse, to the organism and the patient.
Advances in Alzheimer's and Parkinson's Disease
This volume contains the proceedings of the 2005 ADPD conference and is unique in that it deals not only with issues related individually to Alzheimer’s disease and Parkinson’s disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume, which covering topics from immunology, neuroscience, and pharmacology to genetics and molecular biology. Possible future developments in the treatment of Alzheimer’s and Parkinson’s Diseases are also covered.
Current Catalog
First multi-year cumulation covers six years: 1965-70.
The Cambridge Companion to Primo Levi
Primo Levi (1919–87) was the author of a rich body of work, including memoirs and reflections on Auschwitz, poetry, science fiction, historical fiction and essays. In particular, his lucid and direct accounts of his time at Auschwitz, begun immediately after liberation in 1945 and sustained until weeks before his suicide in 1987, has made him one of the most admired of all Holocaust writer-survivors and one of the best guides we have for the interrogation of that horrific event. But there is also more to Levi than the voice of the witness. He has increasingly come to be recognised as one of the major literary voices of the twentieth century. This Companion brings together leading specialists on Levi and scholars in the fields of Holocaust studies, Italian literature and language, and literature and science, to offer a stimulating introduction to all aspects of the work of this extraordinary writer.
Creating Coordination in the Cerebellum
Creating Coordination in the Cerebellum provides a multidisciplinary collection of chapters on the cerebellum with topics covering the entire spectrum from development and molecular neurobiology, cell physiology and plasticity to motor control, system physiology, functional imaging and pathology. The book not only presents novel discoveries obtained with recently developed technologies, but also gives new general concepts in global issues of cerebellar development and functions. By doing so it sets the standard for cerebellar research of the 21st century.* Provides a complete overview of current cerebellar research* Includes color illustrations* Contains contributions from renowned cerebellar scientists
