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Genetic Control of Natural Resistance to Infection and Malignancy
Genetic Control of Natural Resistance to Infection and Malignancy is a collection of papers presented at the 1980 Proceedings of an International Symposium of the Canadian Society for Immunology held in Montreal, Quebec. It provides information about the different models of genetic resistance to various diseases. The book offers an overview of the genetic determination of the susceptibility or resistance to infection and malignancy. It also discusses the importance of genetic resistance not only in the first-line observation of infections and tumors, but also in chemotherapy and immunotherapy. It then explains the genetic control of resistance to parasitic, bacterial, and virus infections, as well as to tumor growth. It further discusses the genetic control of macrophage differentiation and function.
My Life at the Bar and Beyond
My Life at the Bar and Beyond contains a variety of anecdotes by the author, experiences he has had and people he met as a young lawyer in the 60's and later as Chairman of McGill,
Mycobacterium tuberculosis
Tuberculosis once again occupies a special position in the areas of infec tious diseases and microbiology. This disease has been important to mankind since even before biblical times. Tuberculosis has been a major cause of morbidity and mortality in humans, especially in highly ur banized Europe, until a few decades ago. Indeed, this disease became a center of many novels, plays, and operas, since it appeared to be quite popular to have the heroine dying of "consumption. " Most importantly, tuberculosis also became the focus of attention for many investigations during the 19th and even the 20th centuries. Major advances were made in the areas of isolation and identification of M. tuberculosi...
The Future of Life and the Future of our Civilization
This book covers the proceedings of "The Future of Life and the Future of our Civilization" symposium, held in Frankfurt, Germany in May 2005.
Shatterzone of Empires
“Anyone who studies nationalism, genocide, mass violence, or war in these regions, from the Enlightenment through the mid-20th century, needs to read [this].”—Central European History Shatterzone of Empires is a comprehensive analysis of interethnic relations, coexistence, and violence in Europe’s eastern borderlands over the past two centuries. In this vast territory, extending from the Baltic to the Black Sea, four major empires with ethnically and religiously diverse populations encountered each other along often changing and contested borders. Examining this geographically widespread, multicultural region at several levels—local, national, transnational, and empire—and through multiple approaches—social, cultural, political, and economic—this volume offers informed and dispassionate analyses of how the many populations of these borderlands managed to coexist in a previous era and how and why the areas eventually descended into violence. An understanding of this specific region will help readers grasp the preconditions of interethnic coexistence and the causes of ethnic violence and war in many of the world's other borderlands, both past and present.
The Respiratory Burst and Its Physiological Significance
When phagocytes are exposed to a number of different stimuli, they undergo dra matic changes in the way they process oxygen. Oxygen uptake increases markedly, frequently more than 50-fold; the phagocytes begin to produce large quantities of superoxide and hydrogen peroxide; and they immediately begin to metabolize large amounts of glucose by way of the hexose monophosphate shunt. This series of changes has become known as the respiratory burst. It was first believed that the major function of this respiratory burst was to generate powerful antibacterial agents by the partial reduction of oxygen. It is becoming apparent that the respiratory burst has much wider application, and its physiologi...
Phagocytosis: The Host
An accompanying volume (Volume 6) in this series presents strategies of cellular invasion from the viewpoint of the microbe.This filed of study is growing rapidly after a somewhat slow start over recent decades. This collection of invited chapters attempts to reflect current research, and brings together cell biologists, microbiologists and immunologists with disparate interests. However, there is a certain unity, even repetition of key themes, hopefully like a symphony rather than a boring catalogue. It will be evident that editorial bias favors intracellular paratism and medically important organisms. The neutrophil is far more than a supporting player to the macrophage, and some attempt is made to remind the reader of some of its unique skills. To retain a manageable size, the emphasis is on relatively early events such as mutual recognition, cell entry, and response, rather than on longterm changes in gene expression by either host cell or pathogen. Viruses are excluded not because of lack of importance but because of somewhat different research approaches, although it is cytogenes, share common strategies in invasion and intercellular spread.
Standards of Mouse Model Phenotyping
This is the first book in the field of mouse genetics to provide comprehensive and standardized methods for the characterization of laboratory mice. The editor is Director of the German Mouse Clinic and member of the Project Committee of the German National Genome Research Network and provides here a brief introduction to the mouse as a model for diseases and functional analysis of genes and proteins. Throughout, he focuses on the characterization of mouse models using the latest phenotyping methods, with the different areas presented in a clearly structured and easily accessible manner.
