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What kind of science do we need today and tomorrow? In a game that knows no boundaries, a game that contaminates science, democracy and the market economy, how can we distinguish true needs from simple of fashion? How can we distinguish between necessity and fancy? whims How can we differentiate conviction from opinion? What is the meaning of this all? Where is the civilizing project? Where is the universal outlook of the minds that might be capable of counteracting the global reach of the market? Where is the common ground that links each of us to the other? We need the kind of science that can live up to this need for univer sality, the kind of science that can answer these questions. We n...
Reproduction of the original: Pan Tadeusz by Adam Mickiewicz
A founder of and leading thinker in the field of modern ethnobiology looks at the widespread regularities in the classification and naming of plants and animals among peoples of traditional, nonliterate societies--regularities that persist across local environments, cultures, societies, and languages. Brent Berlin maintains that these patterns can best be explained by the similarity of human beings' largely unconscious appreciation of the natural affinities among groupings of plants and animals: people recognize and name a grouping of organisms quite independently of its actual or potential usefulness or symbolic significance in human society. Berlin's claims challenge those anthropologists ...
Kinase drug discovery remains an area of significant interest across academia and in the pharmaceutical industry. There are now around 13 FDA approved small molecule drugs which target kinases and many more compounds in various stages of clinical development. Although there have been a number of reviews/publications on kinase research, this book fills a gap in the literature by considering the current and future opportunities and challenges in targeting this important family of enzymes. The book is forward-looking and identifies a number of hot topics and key areas for kinase drug discovery over the coming years. It includes contributions from highly respected authors with a combined experie...
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Kleine Moleküle für Einsteiger: Dieser für Lehre und Selbststudium gleichermaßen geeignete Band behandelt den computergestützten Entwurf von Wirkstoffen, Enzyminhibitoren, Sonden und Markern für Biomoleküle und führt den Leser bis zum ersten eigenen De-Novo-Design eines funktionellen Moleküls. Gestützt auf lange Erfahrung im Molecular-Modeling-Umfeld erläutern die Autoren, welche Fragen mit den beschriebenen Methoden beantwortet werden können (und welche nicht).
This book is a state-of-the art review of new therapeutic strategies towards treatments for T2D.