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Transduction in Biological Systems
The present volume originated from the workshop "Transduction in Biological Sys tems," held at the Marine Biological Station of the Universidad de Valparaiso, Mon temar, Chile, May 23-30, 1988, and contains contributions from most of the partici pants in the workshop. The title of both the workshop and the book reflects accurately the central theme discussed during several days of intense debate and profound intellectual exchange in the peaceful environment offered by the central coast of Chile. It was apparent that the workshop was a great success-a sentiment expressed by many seasoned attendees, some of whom dared opinions as strong as "It was the best ever." There is no single reason to e...
Ionic Channels in Cells and Model Systems
This book is based on a series of lectures for a course on ionic channels held in Santiago, Chile, on November 17-20, 1984. It is intended as a tutorial guide on the properties, function, modulation, and reconstitution of ionic channels, and it should be accessible to graduate students taking their first steps in this field. In the presentation there has been a deliberate emphasis on the spe cific methodologies used toward the understanding of the workings and function of channels. Thus, in the first section, we learn to "read" single channel records: how to interpret them in the theoretical frame of kinetic models, which information can be extracted from gating currents in re lation to the ...
Pumps, Transporters, and Ion Channels
This book is a compilation of articles based on some of the talks given at the Centro de Estudios Cientificos (CECS) in Valdivia during the course of a celebration to th mark the 60 birthdays of Ramon Latorre and Enrico Stefani. Ramon Latorre is one of the most outstanding figures in channel Biophysics today. The first surprise is that he trained as a Biochemist! He soon, however, became a biophysicist through his work with Guayo (Eduardo) Rojas who guided him during his Ph. D thesis in the Laboratorio de Fisiologia Celular in Montemar. His work at N.I.H with Gerald Eherenstein and Harold Lecar constitutes one of the milestones of single ion channel Biophysics. This classical work, done in p...
International Review of Cell and Molecular Biology
International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. - Authored by some of the foremost scientists in the field - Provides up-to-date information and directions for future research - Valuable reference material for advanced undergraduates, graduate students and professional scientists
From Ion Channels to Cell-to-Cell Conversations
Ion channels allow us to see nature in all its magnificence, to hear a Bach suite, to smell the aroma of grandmother's cooking, and, in this regard, they put us in contact with the external world. These ion channels are protein molecules located in the cell membrane. In complex organisms, cells need to communicate in order to know about their metabolic status and to act in a coordinate manner. The latter is also accomplished by a class of ion channels able to pierce the lipid bilayer membranes of two adjacent cells. These intercellular channels are the functional subunits of gap junctions. Accordingly, the book is divided in two parts: the first part is dedicated to ion channels that look to...
Physical Properties of Biological Membranes and Their Functional Implications
This book was originated from a series of lectures given in a course on the physical properties of biological membranes and their functional implica tions. The course was intended to allow students to get acquainted with the physical techniques used to study biological membranes. The experience was valuable and we feel that a detailed description of the procedures used and of various examples of the results obtained allowed many students to become familiar with a theme that is not often part of regular courses on membrane physiology or biophysics. This book is designed as a tutorial guide for graduate students interested in understanding how physical methods can be utilized to study the prop...
Calcium
Calcium's importance in health and disease is clear when listing its multiple roles in the body, this edited volume will pool knowledge across scientific disciplines in a way that increases its applicability to a wide range of audiences and fills the gap identified in providing comprehensive synopses of food substances.
The Patagonian Icefields
The majesty of the icefields is beyond description. He who has been fortunate to be there once, remains bound forever. To a theoretical physicist working on black holes the icefields produce a familiar vertigo, the instinctive certainty of being confronted with something so simple and beautifully extreme that it must be of importance. The meeting whose proceedings are contained in this volume was conducted onboard of a vessel that went to the icefields, and the participants could literally set foot on them. It was expected that, for those who had not been there before, this would constitute a ritual of initiation. And so it did. For this reason we like to refer to the meeting as an expeditio...
Quantum Mechanics of Fundamental Systems
This volume examines the latest advances emerging from the theoretical exploration into the quantum mechanical structure of our universe. It will be of interest to researchers dealing with strings, quantum fields, gauge theory, and quantum gravity.
