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This open access book provides a concise yet comprehensive overview on how to build a quality management program for hematopoietic stem cell transplantation (HSCT) and cellular therapy. The text reviews all the essential steps and elements necessary for establishing a quality management program and achieving accreditation in HSCT and cellular therapy. Specific areas of focus include document development and implementation, audits and validation, performance measurement, writing a quality management plan, the accreditation process, data management, and maintaining a quality management program. Written by experts in the field, Quality Management and Accreditation in Hematopoietic Stem Cell Transplantation and Cellular Therapy: A Practical Guide is a valuable resource for physicians, healthcare professionals, and laboratory staff involved in the creation and maintenance of a state-of-the-art HSCT and cellular therapy program.
This text aims to provide simplified practical guidelines to start a hematopoietic stem cell transplantation unit which could be implemented in most centers and countries worldwide. The book also provides guidelines for existing transplantation units to upgrade their practice and implement new policies and procedures, in addition to developing therapies according to latest international standards and regulations. The book covers a wide range of practical implementation tools including HSCT program team structure, building inpatient and outpatient HSCT units, requisite laboratory support for transplantation program, practical aspects of stem cell collection and processing, HSCT program qualit...
This book summarizes the global progress in medical and scientific research toward converting traditionally chronic autoimmune diseases into a drug-free reversible illness using hematopoietic stem cell transplantation (HSCT) and other cellular therapies such as T regulatory cells (Treg), mesenchymal stromal/stem cells, and chimeric antigen receptor T (CAR T) cells in order to reintroduce sustained immune tolerance. This title provides information on different types of stem cells and immune cells; post-transplant immune regeneration; cellular regulatory requirements; ethical and economic considerations; and the advantages and disadvantages of HSCT in the treatment of a variety of autoimmune d...
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In its third edition, this massive reference work lists the final resting places of more than 14,000 people from a wide range of fields, including politics, the military, the arts, crime, sports and popular culture. Many entries are new to this edition. Each listing provides birth and death dates, a brief summary of the subject's claim to fame and their burial site location or as much as is known. Grave location within a cemetery is provided in many cases, as well as places of cremation and sites where ashes were scattered. Source information is provided.
A complete guide to Dáil, Seanad & Presidential elections in Ireland in 2011, including comprehensive background & historical information.
The first comprehensive account to record and analyze all deaths arising from the Irish revolution between 1916 and 1921 "A monumental new book [and] an incredible piece of research. . . . Formidable, authoritative and handsomely produced, The Dead of the Irish Revolution is a fitting memorial."--Andrew Lynch, Irish Independent "Will surely serve as the indispensable reference work on this topic for the foreseeable future. . . . A truly remarkable feat of close scholarship and calm exposition."--Gearoid O Tuathaigh, Irish Times Weekend This account covers the turbulent period from the 1916 Rising to the Anglo-Irish Treaty of December 1921--a period which saw the achievement of independence f...
In 1998, a determined Waterford hurling team made their way to their first All-Ireland semi-final in almost forty years, their sights firmly set on the final, which would be their first since 1963.But destiny conspired against them and they lost. Over the next twelve years they would, time and time again, play spell-binding hurling, reach the Semi-Finals seven times, Player of the Year Awards and multiple All-Star honours and come agonisingly close to winning one of the biggest prizes in Irish sport. In The Ecstasy and the Agony, Damien Tiernan goes behind the scenes and takes an unflinchingly honest look at how such a great team can come so close to major triumphs but still walked away with...
This first open access European CAR-T Handbook, co-promoted by the European Society for Blood and Marrow Transplantation (EBMT) and the European Hematology Association (EHA), covers several aspects of CAR-T cell treatments, including the underlying biology, indications, management of side-effects, access and manufacturing issues. This book, written by leading experts in the field to enhance readers’ knowledge and practice skills, provides an unparalleled overview of the CAR-T cell technology and its application in clinical care, to enhance readers’ knowledge and practice skills.
Raw materials have been essential in the development of all human societies through history and moving into a greener, more carbon-lean future we become increasingly reliant on access to a growing number of raw materials. Minerals for new technologies improving the quality of our lives and the environment are the building blocks of the new Green Stone Age. This Special Publication presents ongoing research and mapping programmes focusing on minerals needed for the transformation to greener societies. In addition to new exploration models and shared geological information on the different prospective currently mined areas, the notion of criticality in different countries is discussed and examples of ongoing national and cross-country research and mapping programmes are presented. In addition to the resource/reserve and technical-economic aspects, the social and environmental dimensions are also a focus in some of the contributions, as holistic approaches to the exploration and exploitation of critical minerals and materials are needed to fulfil the green transition and goals for the Green Stone Age.