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Coastal Hydrogeology
Offers a comprehensive volume discussing groundwater problems in coastal areas, spanning fundamental science to practical water management.
Public Policymaking in a Globalized World
The inexorable advent of globalization has transformed the public policymaking process into a multi-faceted challenge that transcends traditional policymaking boundaries and forces scholars, experts, and practitioners to redefine their field in terms of both theory and practice. While every policy dilemma has a specific location in time and space, most significant policy issues— climate change, food and water, economic development, global pandemics, terrorism and violence, and migration, to name just a few—now require a collective framing of the problem and a collaborative effort to take effective action. The essays in Public Policymaking in a Globalized World offer valuable insights into how policymaking is evolving from a circumscribed field of inquiry into a truly global dialogue that can help stakeholders to focus on key issues that threaten the survival of our planet.
A Time for Metabolism and Hormones
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
Polymer Biomaterials in Solution, as Interfaces and as Solids
The articles collected in this publication have previously been published in eight special issues of the Journal of Biomaterials Science, Polymer Edition, in honour of Dr. Allan S. Hoffman, who is known as a pioneer, a leader and a mentor in the field of biomaterials. The papers from renowned scientists from all parts of the world, representing the
Post-Fotoğraf
Dijitalleşmeyle birlikte fotoğraf alanında yaşanan paradigma kaymalarının günümüzdeki durumuna ilişkin tartışmaları içeren bu kitap, “post-fotoğraf” bağlamında güncel perspektifleri okura sunmakta. Fotoğrafı, bellek, ironi, hümanizm, hakikat, siber kültür, avangart, hayal gücü gibi geniş bir tartışma alanında ele alan metinler, bir yandan spesifik vurguları içinde barındırırken bir yandan da post-fotoğraf kavramsalına açıklık getirmeyi amaçlıyor.
DNA and Cell Biology
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The Genetics of Obesity
This book provides a comprehensive compilation of the evidence available regarding the role of genetic differences in the etiology of human obesities and their health and metabolic implications. It also identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health. Leading researchers in their respective fields present contributed chapters on such topics as etiology and the prevalence of obesities, nongenetic determinants of obesity and fat topography, and animal models and molecular biological technology used to delineate the genetic basis of human obesities. A major portion of the book is devoted to human genetic research and clinical observations encompassing adoption studies, twin studies, family studies, single gene effects, temporal trends and etiology heterogeneity, energy intake and food preference, energy expenditure, and susceptibility to metabolic derangements in the obese state. Future directions of research in the field are covered in the book as well.
Micro-, Meso- and Macro-Connectomics of the Brain
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Metal Ions in Neurological Systems
Metal ions in the brain are a necessity as well as a poison. The presence of metal ions in the active sites of biological catalysts or metalloproteins and in the biological functioning of nucleic acids is very well documented and they are required for brain activity. On the other hand, metals are very effective in generating oxidative stress. This effect does not only play a role in immunology but also is the root of practically all neurodegenerative disorders by inducing disease via the death of neurons. Managing metal ions in the brain could therefore be an important strategy in the search for therapeutic agents used in the treatment of neurodegenerative diseases. This new title gives an overview to key topics in the area of metal ions in the brain. It focuses on the role of metal ions in neurological systems by describing their advantageous functions as well as their poisonous features. It is therefore of interest for scientists in biochemistry and biophysics, physiology, toxicology as well as for physicians focused on this topic.
