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Research on cannabis and sleep is emerging with promising results. This book offers current and comprehensive knowledge on cannabinoid research results in connection with sleep. The volume covers aspects of the hemp plant Cannabis sativa, the pharmacology of cannabinoids, neurobiology and pharmacology of sleep and wakefulness, and the benefits and side effects of cannabis on the central nervous system. It further discusses the putative therapeutical properties of cannabinoids and endocannabinoids and their potential for the treatment of sleep disorders such as insomnia, obstructive sleep apnea, REM sleep behavior disorder, and restless legs syndrome. The book is written by medical and scientific experts in this field and intended for researchers from a range of disciplines such as biomedicine, biology, neurosciences, clinical medicine, neurology, and pharmacology.
The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field and shed light on the many brain disorders in which this biological system is involved. Written by world-leading experts in the field, the topics covered in this book will have a positive impact on the area of molecular biology, including, but not limited to, cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics. Provides an introduction to endocannabinoids in the central nervous system and an overview to their functions in the brain Presents information on neurobiological and cellular studies on the role of the cannabinoid signaling system and its implications in human diseases Includes well-written overviews of the basics of endocannabinoid system structure and function Contains well-illustrated material, with diagrams, charts, and tables Explores compelling case studies and their application to chapters written by experts
The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle provides the first comprehensive overview on the molecular methodologies used to evaluate sleep while also examining the cellular, biochemical, genetic, and therapeutic aspects of the sleep-wake cycle. There have been profound changes in the landscape of approaches to the study of sleep – mainly in the areas of molecular biology and molecular techniques. With this great focus on using multidisciplinary molecular methods, chapters address significant advances in the molecular mechanisms underlying sleep and the techniques researchers use to study this phenomenon. Written by world-leading experts in the ar...
Methodological Approaches for Sleep and Vigilance Research examines experimental procedures used to study the sleep-wake cycle, with topics covered by world leaders in the field. The book focuses on techniques commonly used in the sleep field, including polysomnography, electrophysiology, single- and multi-unit spiking activity recording, brain stimulation, EEG power spectra, optogenetics, telemetry, and wearable and non-wearable tracking devices. Further chapters on imaging techniques, questionnaires for sleep assessment, genome-wide association studies, artificial intelligence and big data are also featured. This discussion of significant conceptual advances into experimental procedures is suitable for anyone interested in the neurobiology of sleep. Discusses current sleep research methodologies for experienced scientists Focuses on techniques that allow measurement or assessment for the sleep-wake cycle Outlines mainstream research techniques and experimental characteristics of their uses Includes polysomnography, deep brain stimulation, and more Reviews sleep-tracking devices, EEG and telemetry Covers artificial intelligence and big data in analysis
This volume highlights the recent advances in the understanding of the endocannabinoid system and the likely benefit from the therapeutic effects of cannabinoid treatment in a variety of health issues. Archeological evidence has shown that Cannabis has a long history of use for multiple purposes, including the treatment of medical conditions. The primary active constituent of the hemp plant Cannabis sativa, delta 9-tetrahydrocannabinol (Δ9-THC), causes euphoria, enhancement of sensory perception, tachycardia, antinociception, difficulties in concentration and impairment of memory, among other effects. Despite these undesirable effects, signaling is mostly inhibitory and suggests a putative role for cannabinoids as therapeutic agents by managing several diseases where inhibition of neurotransmitter release would be beneficial. The themes of this book have been edited and written by world-leaders in the field, The contents of the volume aims at readers from a range of academic and professional disciplines, such as biomedicine, several areas of biology, neurology, clinical medicine and pharmacy.
The endocannabinoid system comprises at least two G-protein-coupled receptors (the cannabinoid CB1 and CB2 receptors) activated by marijuana’s psychoactive principle ∆9-tetrahydrocannabinol (THC) and the endogenous ligands known as endocannabinoids. The apex of endocannabinoid research seems to have been reached with the clinical development, and also in some cases, the marketing, of synthetic or natural pharmaceuticals targeting this signalling system, which followed the understanding of the physiological and pathological role of endocannabinoids in several conditions, a role that was investigated first in rodent experimental models and then in humans. Endocannabinoids: Molecular, Pharm...
The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field, and shed light on the many brain disorders this biological system is involved in. Written by world-leading experts in the field, the topics covered in this book will have a positive impact in the area of molecular biology, including but not limited to cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics. An introduction to endocannabinoids in the central nervous system and an overview to their functions in the brain Provides information on neurobiological and cellular studies on the role of the cannabinoid signalling system and its implications in human diseases Includes well-written overviews of the basics of endocannabinoid system structure and function written by expert authors from all over the world. Well-illustrated material, with diagrams, charts, and tables Contains compelling case studies and chapters written by world experts
This book offers a comprehensive but highly readable compilation of papers on the role of dopamine in sleep and sleep disorders. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from established theories to the latest research advances. Accordingly, it represents an interdisciplinary, cutting-edge guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral sleep medicine specialists.
Medicinal Usage of Cannabis and Cannabinoids offers readers a comprehensive reference on the medical usage and symptom relief provided by these compounds in a variety of disorders. With coverage of neurological diseases like Alzheimer’s and Parkinson’s, and a wide range of other afflictions including depression, anxiety, nausea and cancer, this broad coverage allows readers to learn about symptom control, along with the physiological, psychological and pharmacological effects of these compounds. Unique case reports are provided as well. This volume provides a platform for research on the use of these compounds in improving patient care, brain function and neurological dysfunction. Summarizes the medicinal usage of cannabis and cannabinoids in a variety of conditions Contains chapter abstracts, key facts, a dictionary and a summary Examines symptom control of conditions such as depression, anxiety and sleep Discusses cannabis usage in Alzheimer’s, Parkinson’s, Multiple Sclerosis and cancer Features case reports and chapters on the physiological, psychological and pharmacological effects
This book can change the way you think. Literally. “This informative, accessible cookbook will be a boon to health-conscious eaters.” —Publishers Weekly If you struggle with focus and memory lapses, mental fog, or stress—or if you simply want to optimize your mental performance and protect your brain health—Smart Plants is a must read. Written by New York Times bestselling author and natural-food chef Julie Morris, whose name has become synonymous with “superfoods” and “wellness,” this groundbreaking book reveals the dietary secrets to better brain performance. Combining scientific research with the wisdom of ancient remedies, Smart Plants showcases an exciting array of cognition-enhancing plants—from everyday foods to natural nootropics (edibles that can improve memory, learning, and problem solving). Morris’s 65 mouthwatering, beautifully illustrated recipes make it easy to incorporate these powerful foods into your daily diet. Feed your brain with such palate-pleasing dishes as Berry-Almond Amaranth Porridge, French Lentils with Roasted Radishes, Fig & Hazelnut Wild Rice Salad, Garlicky Butter Bean Soup with Kale, Matcha Custard with Wild Berries, and more!