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Intestinal Microbiome: Functional Aspects in Health and Disease
The intestinal microbiome is especially important during the first thousand days of life. Exposure to microbes in utero significantly impacts fetal development, in part through epigenetic processes and in part through hormonal influences which cause a change in the mother's intestinal microbiome. The nature of delivery and perinatal antibiotic treatment, as well as diet (especially in the postpartum period), can also influence initial microbial colonization and the development of appropriate intestinal defense mechanisms. These, in turn, can affect the expression of allergy, autoimmune disease, and brain function, among other things, later in life. The first part of this publication focuses on the development of the human microbiome in utero and the importance of normal colonization of the newborn gut in immune development and disease prevention. The second section deals with the normal development of gut microbiota and with clinical conditions associated with dysbiosis. The final chapters cover various aspects of human milk evolution and oligosaccharides.
Handbook of Atopic Eczema
State-of-the-art review on atopic eczema, one of the most common skin diseases today. This multi-authored handbook covers all aspects relevant for physicians from various disciplines.
Who are We?
Our genome is littered with scraps of DNA, termed ?junk? DNAs, that serve no apparent purpose. Junk DNAs make up as much as 98.5% of our genome. Scientists believe that some junk DNAs came into existence millions of years ago, when viruses inserted their DNA into that of the human host. There is emerging evidence that suggests that these bits of microbial DNAs may alter our functional genes, impacting our body physiology and behavior.We have been invaded by ?body snatchers? and they are part of us! We could postulate that we are carrying a large number of DNAs that serve only the DNAs, and we are just a small part of the big picture! There is ample scientific evidence to suggest that, even today, free-living microbes are still manipulating our behaviour and our life at large. They are thriving on our wet skin, in our mouth, and in our intestinal and vaginal tracts. We are perhaps not quite what we think we are.This thought-provoking and inspiring book offers many answers, while at the same time raising many questions for future research.
Probiotic Bacteria and Their Effect on Human Health and Well-Being
Our microflora is an individual personal feature, providing a distinct tag to individuals. However, our intestinal microbiome is strongly affected by genetic, nutritional, and other external factors, and evolves with age. An effect of different microbial patterns on health appears very likely as there seem to be specific changes of intestinal microflora associated with various diseases. Specific microbial tags may thus be used as biomarkers of disease: to diagnose it, to monitor its evolution, and eventually to predict its response to treatment. This scenario opens the opportunity for targeting intestinal microflora using probiotics, both for prevention and treatment of an increasing number of conditions. Probiotic therapy is applied either as an adjunct to other treatments or as primary therapy, and evidence of efficacy is accumulating in several conditions, affecting either the intestine or nonintestinal organs. This publication provides an update on probiotics directed at physicians, biologists, biotechnologists, and researchers working in the food industry and agriculture, as well as in the environmental and basic sciences.
Pediatric Gastrointestinal Disease
This new edition of Pediatric Gastrointestinal Disease is dedicated to the maintenance of a comprehensive approach to the practice of Pediatric Gastroenterology. Considered to be the definitive reference work, this fourth edition has been extensively reviewed. As a result, the size and content of various sections have been modified and new ......
Your Baby's Microbiome
From the Directors of the Award-Winning Documentary Microbirth At least two amazing events happen during childbirth. There’s the obvious main event, which is the emergence of a new human into the world. But there’s another event taking place simultaneously, a crucial event that is not visible to the naked eye, an event that could determine the lifelong health of the baby. This is the seeding of the baby’s microbiome, the community of “good” bacteria that we carry with us throughout our lives. The seeding of the microbiome, along with breastfeeding and skin-to-skin contact, kick-starts the baby’s immune system and helps protect the infant from disease across a lifetime. Researcher...
Breastfeeding and Human Lactation
Human lactation has evolved to produce a milk composition that is uniquely-designed for the human infant. Not only does human milk optimize infant growth and development, it also provides protection from infection and disease. More recently, the importance of human milk and breastfeeding in the programming of infant health has risen to the fore. Anchoring of infant feeding in the developmental origins of health and disease has led to a resurgence of research focused in this area. Milk composition is highly variable both between and within mothers. Indeed the distinct maternal human milk signature, including its own microbiome, is influenced by environmental factors, such as diet, health, bod...
Outside the Box Cancer Therapies
Now in paperback: A thorough, cutting-edge, alternative therapy-focused exploration of Integrative Oncology care. With approximately 40 percent of men and women in the United States being diagnosed with cancer at some point in their lifetime, very few of us escape having cancer touch our lives in some way--whether it is our own life or that of a loved one. Scientific research continues to prove the benefits of nutritional and holistic therapies, yet, for the most part, these approaches to treatment still remain unexplored by the conventional medical establishment. With integrative and holistic healing being sought after and supported by more and more of the general public and medical communi...
GI Microbiota and Regulation of the Immune System
This book covers current trends in the investigation of GI microbiota. It examines the relationship between the microbiota and the immune system from a variety of angles.
