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Walter Isaacson’s #1 New York Times bestselling history of our third scientific revolution: CRISPR, gene editing, and the quest to understand the code of life itself, is now adapted for young readers! When Jennifer Doudna was a sixth grader in Hilo, Hawaii, she came home from school one afternoon and found a book on her bed. It was The Double Helix, James Watson’s account of how he and Francis Crick had discovered the structure of DNA, the spiral-staircase molecule that carries the genetic instruction code for all forms of life. This book guided Jennifer Doudna to focus her studies not on DNA, but on what seemed to take a backseat in biochemistry: figuring out the structure of RNA, a clo...
Nuclear physics is an exciting, broadly faceted field. It spans a wide range of topics, reaching from nuclear structure physics to high-energy physics, astrophysics and medical physics (heavy ion tumor therapy). New developments are presented in this volume and the status of research is reviewed. A major focus is put on nuclear structure physics, dealing with superheavy elements and with various forms of exotic nuclei: strange nuclei, very neutron rich nuclei, nuclei of antimatter. Also quantum electrodynamics of strong fields is addressed, which is linked to the occurrence of giant nuclear systems in, e.g., U+U collisions. At high energies nuclear physics joins with elementary particle phys...
This book provides applications for the revolutionary technique of optogenetics, which combines genetic and optical methods to observe the function of neurons.
This book contains aseries of review papers related to the lectures given at the Third Course on Bioelectrochemistry held at Erice in November 1988, in the framework of the International School of Biophysics. The topics covered by this course, "Charge Separation Across Biomembranes, " deal with the electrochemical aspects of some basic phenomena in biological systems, such as transport of ions, ATP synthesis, formation and maintenance of ionic and protonic gradients. In the first part of the course some preliminary lectures introduce the students to the most basic phenomena and technical aspects of membrane bioelectrochemistry. The remaining part of the course is devoted to the description o...
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Electrified interfaces span from metaVsemiconductor and metaVelectrolyte interfaces to disperse systems and biological membranes, and are notably important in so many physical, chemical and biological systems that their study has been tackled by researchers with different scientific backgrounds using different methodological approaches. The various electrified interfaces have several common features. The equilibrium distribution of positive and negative ions in an electrolytic solution is governed by the same Poisson-Boltzmann equation independent of whether the solution comes into contact with a metal, a colloidal particle or a biomembrane, and the same is true for the equilibrium distribut...
This book starts with the mathematical basis of the theory - i.e. provide a brief sketch of the theory of manifolds and frame bundles, tensors and their transformations, relativistic kinematics, and aspects of non-flat space-time geometries. The definition of relevant physical quantities (torsion, curvature, non-metricity, tetrads, connection fields etc.) and important geometry concepts are also included. The main body of the book is devoted to a detailed derivation of the gauge theory of gravitation for scalar, vector (Proca and Maxwell) and Dirac spinor fields. Alternative approaches based on the Noether theorem and on the spinorial representation of the fields are also addressed, as well as important novel features related to the CCGG framework (Birkhoff theorem, field derivative identities etc.). In the last section of the volume the application of the CCGG theory to cosmology will be set out, resulting in a new understanding of dark energy and inflation.