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Ion Channels
Modern applications of electrophysiologica techniques; Expression of ion channels; Expression of ion channels in Xenopus oocytes; Expression of ion channels using other systems; Reconstruction of ion channels in lipid bilayers; Recording of ion channels of cellular organelles and miroorganisms; Data storage and analysis.
The Cell
A single cell can be a self-sustaining organism or one of trillions in a larger life form. Though visible only with the help of a microscope, cells are highly structured entities that perform a myriad of functions in every living thing and store critical genetic information. This fascinating volume examines the organization of various types of cells and provides an in-depth look at how cells operate alone to generate new cells and act as part of a larger network with others.
Electrical Properties of Cells
DeFelice presents this intricate subject in an easy-to-follow, stepwise fashion: he reviews the fundamentals of electricity; transfers those principles to a biological context; and expands the discussion to encompass the subject's practical dimensions. Clear definitions and intuitive descriptions characterize the presentation, which is complemented by over 150 drawings and graphs. Mathematics is kept to the minimum necessary. The text covers both excitable and non-excitable membranes and includes the plasma membrane as well as intracellular membranes. A unique, `electronics-made-simple' appendix, designed specifically for biologists, treats the operational amplifiers used in patch clamp, and other appendices offer solutions to equations and examples that illustrate principles.
A Journey Into the Nonlinear World
This is a personal story about being involved in the study of nonlinear phenomena for more than half a century. The focus is on the development of ideas and the resulting knowledge. This is the visible part of research, but much is usually hidden. The author describes how the ideas were generated and how an "invisible college" of friends and colleagues has emerged. The presentation is spiced by thoughts about the beauty of science and philosophical considerations on the complex world, where nonlinear interactions play an important role. The book is in some sense a biography but not so much about the personal life of the author -- it is about science and its actors. Based on the author's experience in many European research centres and science policy institutions, it reflects on the development of knowledge in nonlinear dynamics as well as science policy actions over the second half of the 20th century and the first quarter of the 21st century. Graduates and postgraduates interested in the progress of research will find the book particularly engaging.
Exploring the Nervous System
A study of outstanding research in neuroscience and of the researchers during the 20th century with emphasis on the English, Americans, particularly the Rockefeller University students and professors.
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Instruments of Science
With over 300 entries from the ancient abacus to X-ray diffraction, as represented by a ca. 1900 photo of an X- ray machine as well as the latest research into filmless x- ray systems, this tour of the history of scientific instruments in multiple disciplines provides context and a bibliography for each entry. Newer conceptions of "instrument" include organisms widely used in research: e.g. the mouse, drosophila, and E. coli. Bandw photographs and diagrams showcase more traditional instruments from The Science Museum, London, and the Smithsonian's National Museum of American History. Annotation copyrighted by Book News, Inc., Portland, OR
A Handbook of Nobel Laureates in Medicine
While we are fascinated by Noble Prize winners and their giant contributions to our profession, let us also remember the practice of medicine is a delicate mix of science, compassion, care and commitment. I think it is apt to recall this immortal image of a Victorian era British doctor, who is helplessly watching a dying child with Typhoid fever after exhausting all treatments he could administer at that time. Feets away, we can also see the grieving child’s mother and loving father. This canvas was drawn by British painter Sir Luke Fildes in 1891, still surviving in corridors of most medical schools, hauntingly depicting the care and concern of a Doctor towards his ailing patient. It will continue to remind the generation next, the true meaning of the noble profession. Does it sound unreasonable to expect a Doctor with such qualities deserve a Noble prize in the current times?
Shocking Frogs
"... and still we could never suppose that fortune were to be so friendly to us, such as to allow us to be perhaps the first in handling, as it were, the electricity concealed in nerves, in extracting it from nerves, and, in some way, in putting it under everyone's eyes." With these words, Luigi Galvani announced to the world in 1791 his discovery that nervous conduction and muscle excitation are electrical phenomena. The result of more than years of intense experimental work, Galvani's milestone achievement concluded a thousand-year scientific search, in a field long dominated by the antiquated beliefs of classical science. Besides laying the grounds for the development of the modern neuros...
The Electrophysiology of Neuroendocrine Cells
The Electrophysiology of Neuroendocrine Cells explores the role of electrical activity in neuroendocrine cells in stimulus-secretion coupling, sensory mechanisms, and intercellular communication. This comprehensive and concise handbook includes introductory material on the ontogenesis and classification of the neuroendocrine system and describes general electrical properties, voltage-gated ion channels, and the pharmacology of ion channels. By focusing on functional aspects, The Electrophysiology of Neuroendocrine Cells provides research scientists, physicians, and students with a basic understanding of neuroendocrine cells and their similarity to neurones, as well as their relationship to thyroid- or steroid-hormone secreting endocrine cells. The multidisciplinary nature of this book provides readers with a broad perspective on the electrical properties of neuroendocrine cells, and the combination of general information and specialized information makes the book accessible to beginning and advanced readers alike.
