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Epilepsy and Neurodevelopmental Diseases
This topic has been realized in collaboration with Dr. Gabriele Ruffolo, Post Doctoral Researcher at the University of Rome (Sapienza) (ORCID ID: 0000-0002-6554-5496).
Alternatives for Dermal Toxicity Testing
This book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scientific basis, validation status and regulatory acceptance, applications and limitations, available protocols, and potential role within testing strategies. In addition, perspectives from the test developer are presented, for example regarding critical steps in the protocol. The closing section addresses areas that may be of relevance for the future of dermal toxicity safety testing, including the validation and regulatory acceptance of integrated testing strategies, novel complex skin models, and high-throughput screening techniques.
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 498: In vitro Phototoxicity - Reconstructed Human Epidermis Phototoxicity test method
Skin phototoxicity (photoirritation) is defined as an acute toxic response elicited by topically or systemically administered photoreactive chemicals after the exposure of the skin to environmental light. The in vitro reconstructed human epidermis phototoxicity test (RhE PT) is used to identify the phototoxic potential of a test chemical after topical application in reconstructed human epidermis (RhE) tissues in the presence and absence of simulated sunlight.
European Union Encyclopedia and Directory 2023
Thoroughly updated, this extensive reference source provides in-depth information on all matters relating to the European Union (EU): EU energy policy in the context of the Russian Federation’s invasion of Ukraine is covered in depth, as is the impact of the COVID-19 crisis on EU policy; EU citizenship after Brexit is discussed, together with EU migration policy and the EU’s social framework; EU-Africa relations are reviewed, and current issues in overall foreign policy and security are addressed. Key Features: an up-to date chronology of the EU from 1947 to present an A-Z section contains definitions and explanations of organizations, acronyms and terms, and articles on each member stat...
Functional Imaging and Modeling of the Heart
This book constitutes the refereed proceedings of the 7th International Conference on Functional Imaging and Modeling of the Heart, held in London, UK, in June 2013. The 58 revised full papers were carefully reviewed and selected from numerous initial submissions. The focus of the papers is on following topics: image driven modeling, biophysical modeling, image analysis, biophysical modeling, cardiac imaging, parameter estimation, modeling methods, and biomedical engineering.
The Architecture Annual 2006-2007. Delft University of Technology
The themes of this "Arcjitecture Annual" focuses on how the materials, design, construction and running of a building can affect the environment.
European Union Encyclopedia and Directory 2022
Thoroughly updated, this extensive reference source provides in-depth information on all matters relating to the European Union (EU): the events surrounding the United Kingdom’s departure from the EU are covered in depth, as is the EU’s response to the coronavirus COVID-19 crisis; the EU’s migration policy is discussed, together with the EU’s social framework and enlargement policy; EU-Africa relations are reviewed, and current issues in overall foreign policy and security are addressed. Key Features: an up-to date chronology of the EU from 1947 to present an A-Z section contains definitions and explanations of organizations, acronyms and terms, and articles on each member state. Com...
