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Mechanism and Pharmacodynamic Material Basis of Neurodegenerative Disease Therapies
  • Language: en
  • Pages: 168

Mechanism and Pharmacodynamic Material Basis of Neurodegenerative Disease Therapies

Neurodegenerative diseases are debilitating disorders defined as loss of function or progressive destructing structure of the nervous system with high prevalence among the aging population. These diseases mainly include Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS). They are significantly associated with age and degeneration, becoming a devastating global health issue as a result of the growth of mean life expectancy worldwide. Few or no effective treatments are available for age-related neurodegenerative diseases, causing large socioeconomic and personal costs. The last 15 years have seen a boom in the use and in...

Targeting Protein Post-Translational Modifications (PTMs) for Diagnosis and Treatment of Sepsis
  • Language: en
  • Pages: 154
Primary Intracranial Tumors
  • Language: en
  • Pages: 142

Primary Intracranial Tumors

This book covers specific chapters with fundamental and current concepts about the main primary intracranial tumors, aimed at general neurosurgeons, neurologists, oncologists, radiotherapists, and residents. They are everyday situations from the subspecialist routine that can become challenging for professionals outside referenced centers or working alone.

AACR 2019 Proceedings: Abstracts 1-2748
  • Language: en
  • Pages: 2881

AACR 2019 Proceedings: Abstracts 1-2748

American Association for Cancer Research 2019 Proceedings: Abstracts 1-2748 - Part A

Intermolecular Cross-talk in Tumor Metastasis
  • Language: en
  • Pages: 322

Intermolecular Cross-talk in Tumor Metastasis

  • Type: Book
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  • Published: 1999
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  • Publisher: IOS Press

Metastasis of tumours is a sequence of events taking place after the appearance of a primary tumour. The potency of a tumour to metastasise greatly depends on the molecular interactions between tumour components (cellular differentiation and heterogeneity, surface antigenic determinants etc.) and the micro-environment. The complexity and diversity in the composition of tissue micro-environment is in great extent determining the metastatic behaviour or a primary tumour. Extracellular matrix composition, rearrangement of cytoskeleton, cell antigenicity , expression of metastasis-related novel genes, cell adhesion and novel therapeutical approaches such as blockage of angiogenesis, are the major topics discussed in detail in this volume.

Healthcare and Medical Devices
  • Language: en
  • Pages: 309

Healthcare and Medical Devices

Healthcare and Medical Devices Proceedings of the 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022), July 24–28, 2022, New York, USA

The Metabolic Approach to Cancer
  • Language: en
  • Pages: 409

The Metabolic Approach to Cancer

The Optimal Terrain Ten Protocol to Reboot Cellular Health Since the beginning of the twentieth century, cancer rates have increased exponentially--now affecting almost 50 percent of the American population. Conventional treatment continues to rely on chemotherapy, surgery, and radiation to attack cancer cells. Yet research has repeatedly shown that 95 percent of cancer cases are directly linked to diet and lifestyle. The Metabolic Approach to Cancer is the book we have been waiting for--it offers an innovative, metabolic-focused nutrition protocol that actually works. Naturopathic, integrative oncologist and cancer survivor Dr. Nasha Winters and nutrition therapist Jess Higgins Kelley have ...

Neuroimaging in Parkinson’s Disease and Parkinsonism
  • Language: en
  • Pages: 312
Brain Imaging Methods Editor’s Pick 2021
  • Language: en
  • Pages: 440

Brain Imaging Methods Editor’s Pick 2021

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