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This concise, yet practical handbook will aid in supporting the diagnosis, treatment, and long-term management of autism, including behavioral therapies, current clinical trials, and emerging pharmaceutical treatments. Autism spectrum disorder (ASD) is a developmental disorder characterised by disturbance in language, perception, and social skills that affects an estimated 1–2 per 1,000 people worldwide (although the number is as high as 20 per 1000 in the US). While studies have suggested a disturbance in neural metabolism in patients with ADS, the exact cause of the ASD still remains unknown. In 2013, a single indication of ASD, which united several related conditions (ie, classical autism, Asperger’s syndrome, Fragile X Syndrome, Landau-Kleffner Syndrome, Rett syndrome, childhood disintegrative disorder, and PDD-NOS), was included in the fifth edition of the Diagnostic and Statistical Manual of Mood Disorders for the first time in order to support more standardized diagnoses.
This concise, yet practical handbook will aid in supporting the diagnosis, treatment, and long-term management of autism, including behavioral therapies, current clinical trials, and emerging pharmaceutical treatments. Autism spectrum disorder (ASD) is a developmental disorder characterised by disturbance in language, perception, and social skills that affects an estimated 1–2 per 1,000 people worldwide (although the number is as high as 20 per 1000 in the US). While studies have suggested a disturbance in neural metabolism in patients with ADS, the exact cause of the ASD still remains unknown. In 2013, a single indication of ASD, which united several related conditions (ie, classical autism, Asperger’s syndrome, Fragile X Syndrome, Landau-Kleffner Syndrome, Rett syndrome, childhood disintegrative disorder, and PDD-NOS), was included in the fifth edition of the Diagnostic and Statistical Manual of Mood Disorders for the first time in order to support more standardized diagnoses.
Explaining how to diagnose autism by providing examples and guidelines for evaluation and testing of individuals, this guide helps practitioners to evaluate the appropriate role of various medications for specific target symptoms and individuals. It also describes complementary and alternative therapies and explores promising new avenues of treatment.
This book is a printed edition of the Special Issue "The Identification of the Genetic Components of Autism Spectrum Disorders 2017" that was published in IJMS
This book focuses on the emerging and expanding areas of research on ASD and their potential to lead to better diagnosis and more effective therapies. These areas include innovative and integrative approaches to genetic/genomic analyses and investigations of epigenetic contributions, including the role of noncoding RNAs, DNA methylation, alternative splicing, RNA editing, and faulty translation in gene regulation and expression, metabolic and immune dysfunction, co-morbidities, as well as hormonal and gene-environment interactions that may increase risk for ASD.Within each chapter, experts review cutting-edge research as well as provide their perspective on the future of research in their re...
Autism is an emerging area of basic and clinical research, and has only recently been recognized as a major topic in biomedical research. Approximately 1 in 150 children are diagnosed as autistic, so it is also an intense growth area in behavioral and educational treatments. Financial resources have begun to be raised for more comprehensive research and an increasing number of scientists are becoming involved in autism research. In many respects, autism has become a model for conducting translational research on a psychiatric disorder. This text provides a comprehensive summary of all current knowledge related to the behavioral, experiential, and biomedical features of the autism spectrum di...
Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the ...
Published annually, volumes in this series provide readers with updates of clinical trial results, impacts of trials on guidelines and evidence-based practice, advances in trial methodologies, and the evolution of biomarkers in trials. The series focuses on trials in neurotherapeutics, including disease-modifying and symptomatic agents for neurological diseases, psychopharmacological management of neurologic and psychiatric illnesses, and non-drug treatments. Each paper is authored by a leader in the area of neurotherapeutics and clinical trials, and the series is guided by an editor-in-chief and editorial board with broad experience in drug development and neuropsychopharmacology. Progress in Neurotherapeutics and Neuropsychopharmacology is an essential update of trials in all aspects of the management of neurologic and neuropsychiatric disorders, and will be an invaluable resource for practising neurologists as well as clinical and translational neuroscientists. This volume was first published in 2006.