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This volume contains the lectures of invited speakers on the following topics: Collective excitations at zero and finite temperature; Algebraic and geometric symmetric nuclear models; Fundamental symmetries in nuclear physics; Fast rotating nuclei; Nuclei far from stability; Nuclear multifragmentation; Nuclear astrophysics; Subnucleonic degrees of freedom; Relativistic effects in nuclear physics; Quark-gluon plasma physics; Order and chaos in nuclear physics; Nuclear physics and atomic aggregates; Applied nuclear physics.
Recent developments in nonlinear dynamics has significantly altered our basic understanding of the foundations of classical physics. However, it is quantum mechanics, not classical mechanics, which describes the motion of the nucleons, atoms, and molecules in the microscopic world. What are then the quantum signatures of the ubiquitous chaotic behavior observed in classical physics? In answering this question one cannot avoid probing the deepest foundations connecting classical and quantum mechanics. This monograph reviews some of the most current thinkings and developments in this exciting field of physics.
This book presents a collection of major developments in chaos systems covering aspects on chaotic behavioral modeling and simulation, control and synchronization of chaos systems, and applications like secure communications. It is a good source to acquire recent knowledge and ideas for future research on chaos systems and to develop experiments applied to real life problems. That way, this book is very interesting for students, academia and industry since the collected chapters provide a rich cocktail while balancing theory and applications.
This book consists of pedagogical contributions on currently viable theories of nuclear structure and critical evaluative comments on each of these theories.
"New Trends in Nuclear Collective Dynamics" emphasizes research toward understanding collective and statistical aspects of nuclear dynamics. Well-known lecturers from centers of nuclear research present reviews of recent developments. The topics covered are: -order and chaos in finite quantum systems -dissipation in heavy-ion collisions -collective motionsin warm nuclei -time-dependent mean-field theory with collision terms -nuclear fission and multi-dimensional tunneling -large-scale collective motion
Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells. Thus, protein kinases play key roles in the regulation of cell life or death decisions. Protein kinases are frequently a driving factor in a variety of human diseases including aging and cellular senescence, immune system and endothelial dysfunctions, cancers, insulin resistance, cholestasis and neurodegenerative diseases, as well as bacterial resistance in persistent infections. Recent developments in quantitative proteomics provide important opinions on kinase inhibitor selectivity and their modes of action in the biological context. Protein Kinase-mediated Decisions Between Life and Death aims to have the reader catch insights about up-to-date opinions on “Protein Kinases” related pathways that threaten human health and life. As “Protein Kinases” are related to many health problems, clinicians, basic science researchers and students need this information. Chapter “Signal Transduction in Immune Cells and Protein Kinases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
This book presents the state-of-art marine metagenome research and explains the method of marine metagenomic analysis in an easy-to-understand manner. Changes in the marine environment due to global warming and pollution have become a major global problem. Maintaining a healthy marine ecosystem requires advanced environmental monitoring and assessment systems. As such, the book presents a novel metagenomic monitoring method, which has been developed for comprehensive analyses of the DNA of microorganisms living in seawater to further our understanding of the dynamics of the marine environment. The book can be used as a primer for new researchers and as a manual on experimental methods.
As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes, old and new diseases and adverse conditions. Indeed, complement became a term that almost defies categorization. What was for a long time a subject for a limited number of specialists has now moved into the mainstream of experimental and clinical immunology. In 1973 I visited the Basel Institute of Immunology and met its director, the eminent scientist and Nobel laureate Nils Jerne. When I entered his office he greeted me with the following word...
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Modifications in biomacromolecules (DNA, RNA, and proteins) are important molecular events in different pathophysiological conditions. These modifications include DNA modifications, RNA post-transcriptional modifications, and protein post-translational modifications that regulate the structures and functions of biomacromolecules and even the entire biological system. In addition, they are associated with a wide spectrum of diseases. Biomacromolecular modifications are important factors in creating proteoforms that constitute the end-point structural and functional forms of a gene or protein that can be applied for predictive, preventive, and personalized medicine (PPPM) as well as precision medicine (PM).