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Ischemic heart disease is the leading cause of morbidity and mortality in the developed world. The high metabolism and oxygen demand of the cardiac myocardium depends on both a high blood flow and a rich capillary density. For this reason, the growth of the coronary vasculature is vital, not only in early development, but also in the adult faced with various stresses. Novel technologies have enabled the discovery of the molecular mechanisms underlying the growth and assembly coronary vessels, and this volume covers the hierarchy of the coronary vasculature from its embryonic origins through its postnatal growth, adulthood, and senescence. Chapters address normal coronary development, coronar...
Having worked closely with Harry S. Truman in the triumphant campaign of 1948, Jonathan Daniels believed that President Truman was an "everyday" American, an ordinary human who aspired to greatness and achieved it. Thus, it was Daniels's intention that The Man of Independence not be a conventional biography; rather, he wanted it to reveal in real terms "the Odyssey of the 'everyday' American through our times." As a result, this comprehensive work not only presents Truman's life, it also details the development of the America in which the president grew up. Truman spent his youth and his political life believing that old- fashioned, determined conservatism was vital to the preservation of pe...
A uniquely intimate portrait of John F. Kennedy, this humbling and touching memoir uncovers the private man from the matchless vantage point of a longtime childhood friend.
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