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Substance Use Disorder: Above and Beyond Addiction
Substance Use Disorder (SUD) is a mental disorder that causes an individual to compulsively consume legal or illegal drugs such as alcohol, opioids, methamphetamine, marijuana, and medications, despite harmful consequences. According to the World Health Organization (WHO), alcohol causes 5.1 % of the global burden of disease, and harmful drinking behavior is associated with more than 200 diseases and injury conditions. According to the UN Office on Drugs and Crime, about 200 million people are addicted to cocaine, cannabis, opioids and sedative-hypnotics.
Challenges In Information Technology Management - Proceedings Of The International Conference
This volume contains some research papers from the International Conference on Information Technology and Management organized by the Hong Kong Polytechnic University, in conjunction with the Institute of Systems Management (ISM). It comprises 30 selected and refereed papers in the development of enabling technologies, electronic commerce and knowledge management, and IT systems and applications. These papers feature the results of the latest research in the areas of information systems, enabling technologies, and business management, as well as potential applications in industries including education, finance, logistics, medical tourism, and IT services.
The Role of Tumor Microenvironment in the Development, Treatment and Prognosis of Hepatocellular Carcinoma
Primary liver cancer (PLC), including hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), and other rare tumors, is the third leading cause of cancer-related mortality. Of all primary liver cancer, HCC is the most common type. Evidence has accumulated that the tumor microenvironment (TME) plays a key role in fostering or restraining tumor development. The tumor microenvironment (TME), which includes molecular, cellular, extracellular matrix(ECM), and vascular signaling pathways, is a complex ecosystem. The interaction between the tumor microenvironment and cancer cells can enhance the malignant properties of tumors, including proliferation, angiogenesis, metastasis, and therapy resistance. In addition, the tumor microenvironment can also lead to abnormal angiogenesis and promote immunosuppression. HCC has been resistant to targeted therapy and immunotherapy. Therefore, further study of the tumor microenvironment of HCC may be helpful for the development of therapeutic methods for HCC.
Challenges in Information Technology Management
This volume contains some research papers from the International Conference on Information Technology and Management organized by the Hong Kong Polytechnic University, in conjunction with the Institute of Systems Management (ISM). It comprises 30 selected and refereed papers in the development of enabling technologies, electronic commerce and knowledge management, and IT systems and applications. These papers feature the results of the latest research in the areas of information systems, enabling technologies, and business management, as well as potential applications in industries including education, finance, logistics, medical tourism, and IT services.
China: A Historical Geography of the Urban
This book offers a unique contribution to the burgeoning field of Chinese historical geography. Urban transformation in China constitutes both a domestic revolution and a world-historical event. Through the exploration of nine urban sites of momentous change, over an extended period of time, this book connects the past with the present, and provides much-needed literature on city growth and how they became complex laboratories of prosperity. The first part of this book puts Chinese urban changes into historical perspective, and probes the relationship between nation and city, focusing on Shanghai, Beijing and Changchun. Part two deals with the relationship between history and modernity, concentrating on Tunxi, a traditional trade center of tea, New Villages in Shanghai and street names in Taipei and Shanghai. Part three showcases the complexities of urban regeneration vis-à-vis heritage preservation in cities such as Datong, Tianjin and Qingdao. This book offers an innovative interdisciplinary and international perspective, which will be of interest to students and scholars of Chinese urban studies, as well Chinese politics and society.
Chinese Epigraphy in Singapore, 1819–1911
The history of Singapore’s Chinese community is carved in stone and wood: in the epigraphic record of 62 Chinese temples, native-place associations, clan and guild halls, from 1819 to 1911. These materials include temple plaques, couplets, stone inscriptions, stone and bronze censers, and other inscribed objects found in these institutions. They provide first-hand historical information on the aspirations and contributions of the early generation of Chinese settlers in Singapore. Early inscriptions reveal the centrality of these institutions to Chinese life in Singapore, while later inscriptions show the many ways that these institutions have evolved over the years. Many have become deeply engaged in social welfare projects, while others have also become centers of transnational networks. These materials, available in English with Chinese translation, open a window into the world of Chinese communities in Singapore. These cultural artifacts can also be appreciated for their exceptional artistic value. They are a central part of the heritage of Singapore.
Three Kingdoms and Chinese Culture
This is the first book-length treatment in English of Three Kingdoms (Sanguo yanyi), often regarded as China's first great classical novel. Set in the historical period of the disunion (220–280 AD), Three Kingdoms fuses history and popular tradition to create a sweeping epic of heroism and political ambition. The essays in this volume explore the multifarious connections between Three Kingdoms and Chinese culture from a variety of disciplines, including history, literature, philosophy, art history, theater, cultural studies, and communications, demonstrating the diversity of backgrounds against which this novel can be studied. Some of the most memorable episodes and figures in Chinese lite...
The Richest Old Woman
The first time I met Ward in college, I sat in his back row and watched him flirt with his girlfriend. The second time they met, she was still sitting behind him, and he still came with his girlfriend, but it was not the same as last time. Later, she witnessed the girls beside him changing one after another. On Christmas Day, the two came back from school, and the school was full of lovers holding hands. Lucy asked him in a subtle way: "Would you like to give me an extra girlfriend?" After waiting for half a minute, he didn't respond. Lucy knew that this was a polite refusal. —— You can't fall into the same trap twice. The first time is called naivety, and the second time is called stupi...
