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The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 1-2696 presented on April 17-18, 2016, at the AACR Annual Meeting.
This book is a printed edition of the Special Issue "BioEnergy and BioChemicals Production from Biomass and Residual Resources" that was published in Energies
This guide provides practical information that will assist clinicians involved in the diagnosis, assessment, treatment, and follow-up care of patients with triple-negative breast cancer. After opening chapters on the pathologic evaluation, clinical presentation, genetics, and imaging features, the full range of current treatment approaches is thoroughly reviewed from a multidisciplinary perspective. Readers will find up-to-date information and guidance on surgical management, radiation therapy, tailored adjuvant therapy, neoadjuvant treatment, systemic treatment for metastatic disease, molecular profiling, and targeted therapy. The coverage is completed by discussion of special issues in young women with triple-negative breast cancer and individualization of the management approach in older patients affected with the disease. All healthcare professionals who care for patients with triple-negative breast cancer will find the book to be an invaluable source of expert advice on the issues faced in real-world practice.
Bacterial nanocellulose (BNC), cellulose nanocrystals (CNCs), and cellulose nanofibers (CNFs) are three nanometric forms of the most abundant natural polymer (viz. cellulose), and are currently under the spotlight in numerous fields of modern science and technology. The eco-friendly connotations, peculiar features, and multiple functionalities of these nanoscale cellulosic substrates are being explored to engineer advanced nanocomposites and nanohybrid materials for application in manifold domains, such as mechanics, optics, electronics, energy, environment, biology, and medicine.The aim of this Special Issue titled "Advanced Nanocellulose-Based Materials: Production, Properties, and Applications" is to gather original research and review contributions from the world-leading scientists working with nanocellulose. Thus, research that is representative of the current developments dealing with the production methodologies, properties, and applications of nanocellulose-based materials (e.g., nanocomposites, hybrids, aerogels, hydrogels, films, and fibers) are presented in the Special Issue.
The aim of this Special Issue is to present the latest achievements related to the manufacturing and processing of titanium alloys and titanium-based composites. The subjects of published research articles concern deformation behavior, development of microstructure and properties and special applications of titanium-based materials. The Special Issue contains 21 articles-1 editorial, 18 research articles, 1 review and 1 technical note, written by the authors representing scientific institutions from 13 countries. It provides a wide overview of recent research developments on different aspects of titanium-based materials, which should be useful for researchers and engineers working in this field.
Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a wide range of symptoms and signs, including acute and chronic pelvic pain and infertility. Endometriosis affects approximately 10% of women of reproductive age, and up to 50% of infertile women. The etiopathogenesis of endometriosis still remains controversial: immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.One of the main problems for the management of endometriosis is the significant diagnostic delay: to date, several biomarkers are currently being tested in order to provide a reliable non-invasive diagnosis in case of symptoms and signs suspicious for endometriosis.In addition, ultrasound techniques and magnetic resonance imaging are evolving rapidly, allowing for better accuracy, even with the use of artificial intelligence. Finally, new potential histological makers are helping to correlate the occurrence of endometriosis in different anatomical landmarks, supporting specific pathways to clarify the etiology of the disease.