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Drug Repurposing
Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.
Natural Products and Cancer Drug Discovery
This book, Natural Products and Cancer Drug Discovery, is written by leading experts in natural products in cancer therapy. The first two sections describe new applications of common herbs and foods for treatment of cancer. Section 3 deals with the development of new chemotherapeutics from Cannabis and endophytic fungi. Section 4 presented formulations of natural products for treatment of malignant melanoma. Made-to-order anticancer therapy from natural products using computational and tissue engineering approaches is addressed in the fifth section. It is our hope that this book may motivate readers to approach the evidence of anticancer natural products with an open mind and thereby spark an interest in making further contributions to the cancer treatment efforts.
Evidence-based Strategies in Herbal Medicine, Psychiatric Disorders and Emergency Medicine
This book intends to strike a balance between developments in pharmacotherapy research and the facts that researchers must absorb, as well as link scientific advances with clinical practice so that the management of diseases can be based on sound physiological concepts. Each chapter has been reviewed and new authors have brought up-to-date research to make the book more informative, illustrative, and easy to read. The book focuses on three major areas: Experimental, preclinical, and clinical applications of herbal medicine; Evidence-based strategies in emergency medicine and New approach in management of psychiatric disorders. The first three chapters describe new and modern applications of ...
Anticancer Properties of Fruits and Vegetables
An estimated 12.6 million people are diagnosed with cancer every year and 7.6 million people die of the disease annually. Numerous lines of evidence suggest that lifestyle and nutrition play an important role in cancer development. As for nutrition, diets that are rich in fruits and vegetables have been shown to lower the risk of cancer incidence. In addition, several phytochemicals that are present in fruits and vegetables have been scientifically established to have properties that can prevent and treat this malevolent disease. The primary aim of the book is to educate the public about the benefits of fruits and vegetables as they relate to cancer and their potential to contribute to the p...
Pharmacotherapy
The intent of this book is to provide an overview of current conceptualizations of Pharmacotherapy. The book focuses on three major areas; diagnosis, treatment, and prevention for a wide array of diseases; Cognitive and Psychological disorders (Schizophrenia and Nicotine addiction), Inflammatory disorders (New Chemical anti-inflammatory and Immunotherapy), updated antihypertensive therapy and healing of ulcers with venous origin. A separate chapter is dedicated to the rationality of drug use in earthquake injuries. The last chapter deals with Imaging of potential therapeutic or diagnostic agents in animal models in the early stage of research. We hope this book is useful to a wide range of people, from students first learning about Pharmacotherapy, to advanced clinicians and researchers.
Poisoning
Poisoning has always been a part of human life. For years, poisoning was considered a clinical entity that could be treated and/or prevented. However, in a practical sense, the same method was used for detoxifying or treating all causative agents. Understanding the salient features of different types of poisonings is necessary to develop efficient approaches to early diagnosis, prevention, and treatment, and even for the repurposing of fatal toxic substances for use as therapeutic agents. This book presents the chemical and biological nature as well as the mechanisms of environmental toxins, snake venoms, heavy metals, and bacterial toxins in poisoning and highlights the most recent approaches and theories for prevention, diagnosis, and treatment. It also examines the possible repositioning of highly toxic glycoalkaloids found in potatoes to life-saving anticancer drugs. This book presents a balance between advanced scientific research and the premises that researchers must be able to absorb and apply, as well as links scientific advances with clinical practice so that the management of poisons can be based on sound academic and clinical concepts.
Radiopharmaceuticals
Radiopharmaceuticals - Current Research for Better Diagnosis and Therapy discusses the importance of radiopharmaceuticals and their environmental, pharmaceutical, diagnostic, therapeutic, and research applications. Chapters address such topics as the fundamentals of radiopharmaceutical chemistry and preparation, fabrication, materials manipulation, and characterization of radiopharmaceuticals, applications of radiopharmaceuticals in preclinical studies, radiopharmaceuticals in modern cancer therapy, and new trends in preparation, biodistribution, and pharmacokinetics of radiopharmaceuticals in diagnosis and research.
Advanced Machine Learning Technologies and Applications
This book constitutes the refereed proceedings of the Second International Conference on Advanced Machine Learning Technologies and Applications, AMLTA 2014, held in Cairo, Egypt, in November 2014. The 49 full papers presented were carefully reviewed and selected from 101 initial submissions. The papers are organized in topical sections on machine learning in Arabic text recognition and assistive technology; recommendation systems for cloud services; machine learning in watermarking/authentication and virtual machines; features extraction and classification; rough/fuzzy sets and applications; fuzzy multi-criteria decision making; Web-based application and case-based reasoning construction; social networks and big data sets.
Handbook of Research on Machine Learning Innovations and Trends
Continuous improvements in technological applications have allowed more opportunities to develop automated systems. This not only leads to higher success in smart data analysis, but it increases the overall probability of technological progression. The Handbook of Research on Machine Learning Innovations and Trends is a key resource on the latest advances and research regarding the vast range of advanced systems and applications involved in machine intelligence. Highlighting multidisciplinary studies on decision theory, intelligent search, and multi-agent systems, this publication is an ideal reference source for professionals and researchers working in the field of machine learning and its applications.
Air Pollution Modelling
The air pollution problem inevitably accompanies our human activities. Severe air pollution situations have been reported, especially in emerging countries, and satisfying the air quality standards fully remains an underlying issue. Today, modeling research is one of the more valuable approaches to understanding the behavior of air pollutants, and is useful for regulation-, policy- and decision-making. Such modeling applications range, with regard to horizontal grid resolution, from a few km (local) to hundreds of km (regional), to thousands of km (global). To foster our current scientific knowledge on modeling potentialities and limitations, scientific research related to multi-scale air pollution modeling is collected in this book.
