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Artificial Life and Evolutionary Computation
This book constitutes the refereed proceedings of the 16th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2022, held in Gaeta, Italy, during September 14–16, 2022. The 21 full papers and 3 short papers included in this book were carefully reviewed and selected from 45 submissions. They were organized in topical sections as follows: answer set programming; networks and complex systems, metaheuristics, robotics, and machine learning Chapters 7, 8, and 9 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Artificial Life and Evolutionary Computation
This book constitutes the proceedings of the 15th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2021, held in Winterthur, Switzerland, in September 2022. The 14 full papers and 10 short papers presented in this volume were carefully reviewed and selected from 25 submissions. The papers are organized in the following topical sections: Networks; Droplets, Fluids, and Synthetic Biology; Robot Systems; Computer Vision and Computational Creativity; Semantic Search; Artificial Medicine and Pharmacy; Trade and Finance; Ethics in Computational Modelling. Chapters 4, 5, 6, 7, 22, and 24 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Acute-on-chronic Liver Failure: Systemic Inflammation and Immunosuppression, 2nd edition
Acute-on-chronic liver failure (ACLF) is a fatal disease that develops in the basis of chronic liver diseases due to acute precipitating events. The lack of definite therapies for ACLF other than liver transplantation urges us to investigate its pathophysiological mechanism. It has been recognized that systemic inflammation is a major driver of ACLF. Although the link between systemic inflammation and organ failure has been established, less is known about how systemic inflammation forms and how it impacts on the organ functions. On the other hand, immunosuppression is another facet of immune derangement of ACLF, which leads to secondary bacterial infections and worsens the situation. Howeve...
Immune Profile after Autologous Hematopoietic Stem Cell Transplantation for Autoimmune Diseases: Where Do We Stand?
Autologous hematopoietic stem cell transplantation (AHSCT) was proposed 20 years ago as an alternative therapeutic approach for patients with severe and refractory autoimmune diseases. Since then, this innovative therapy has been successfully used to treat several autoimmune diseases, such as neurological disorders (Multiple Sclerosis), connective tissue diseases (Systemic Sclerosis and Systemic Lupus Erythematous), gastrointestinal inflammatory diseases (Crohn’s Disease) and others (Juvenile Arthritis, Type 1 Diabetes, Vasculitis). Experience in phase I-II and III clinical trials over the years has led to increased safety and efficacy of this procedure. Recent studies have demonstrated su...
