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Artificial Life and Evolutionary Computation
This book constitutes the refereed proceedings of the 16th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2022, held in Gaeta, Italy, during September 14–16, 2022. The 21 full papers and 3 short papers included in this book were carefully reviewed and selected from 45 submissions. They were organized in topical sections as follows: answer set programming; networks and complex systems, metaheuristics, robotics, and machine learning Chapters 7, 8, and 9 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Artificial Life and Evolutionary Computation
This book constitutes the proceedings of the 15th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2021, held in Winterthur, Switzerland, in September 2022. The 14 full papers and 10 short papers presented in this volume were carefully reviewed and selected from 25 submissions. The papers are organized in the following topical sections: Networks; Droplets, Fluids, and Synthetic Biology; Robot Systems; Computer Vision and Computational Creativity; Semantic Search; Artificial Medicine and Pharmacy; Trade and Finance; Ethics in Computational Modelling. Chapters 4, 5, 6, 7, 22, and 24 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
COVID-19 booster vaccination: increasing immunity against life-threatening infection
Although COVID-19 full prime vaccination generates immunity against severe and life-threatening infections, there are still cases of breakthrough infections. This might be due to several causes — such as the fact that full prime vaccination might not generate enough immunity; that immunity wanes over time; or that the elderly, immunocompromised, transplant recipients and people with underlying diseases could suffer severe infections regardless of vaccination. Moreover, emerging new variants of concern (such as Delta or Omicron) that are highly infective and evade immunity could increase breakthrough infection. Booster shots could increase immunity and reduce the likelihood of having severe...
Antibody Repertoire and Graft Outcome Following Solid Organ Transplantation
The first real major breakthrough that laid the basis of HLA antibody detection in the field of solid organ transplantation, came with the introduction of the complement dependent cytotoxicity (CDC) test in 1964 by Terasaki and McClelland. Since then, methods for antibody detection have evolved remarkably from conventional cell-based assays to the current advanced solid phase systems on the Luminex platform, with increasing degree of sensitivity and specificity. The latter have been indispensable for more accurate identification of donor specific HLA antibodies in broadly reactive allo antisera, and to guide donor selection and kidney paired exchange programs through virtual crossmatching, i...
Multi-Pronged Omics Technologies to Understand COVID-19
"COVID-19 and Omics Technologies" is a comprehensive, integrative assessment of recent information and knowledge collected on SARS-CoV-2 and COVID-19 during the pandemic based on omics technologies. It demonstrates how omics technologies could better investigate the infectious disease and propose solutions to the current concerns. The value of multi-omics technologies in understanding disease etiology and host response, discovering infection biomarkers and illness prediction, identifying vaccine candidates, discovering therapeutic targets, and tracing pathogen evolution is discussed in this book. These factors combine to make it a valuable resource to enhance understanding of both "Omics tec...
