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Recent technological advances in single-cell microbiology, using flow cytometry, microfluidics, x-ray fluorescence microprobes, and single-cell -omics, allow for the observation of individuals within populations. Simultaneously, individual-based models (or more generally agent-based models) allow for individual microbes to be simulated. Bridging these techniques forms the foundation of individual-based ecology of microbes (µIBE). µIBE has elucidated genetic and phenotypic heterogeneity that has important consequences for a number of human interests, including antibiotic or biocide resistance, the productivity and stability of industrial fermentations, the efficacy of food preservatives, an...
Modern computing relies on future and emergent technologies which have been conceived via interaction between computer science, engineering, chemistry, physics and biology. This highly interdisciplinary book presents advances in the fields of parallel, distributed and emergent information processing and computation. The book represents major breakthroughs in parallel quantum protocols, elastic cloud servers, structural properties of interconnection networks, internet of things, morphogenetic collective systems, swarm intelligence and cellular automata, unconventionality in parallel computation, algorithmic information dynamics, localized DNA computation, graph-based cryptography, slime mold ...
Current Geographical Publications (CGP) is a non-profit service to the scholarly community initiated in 1938 by the American Geographical Society of New York. Beginning in 2006, the format changed to include the tables of contents of current geographical journals. The journal titles listed link to web pages or PDF scans of the current issue's contents.
»In dieser klarsichtigen, umsichtigen und wunderbar geschriebenen Erkundung der Zeit bietet Burdick nicht weniger als eine völlig neue Sichtweise darauf, was es heißt, Mensch zu sein.« Hanya Yanagihara, Autorin von "Ein wenig Leben" Die Zeit kann dahinkriechen oder rasend schnell verfliegen. Wir wünschen uns alle Zeit der Welt und wissen doch, dass sie irgendwann abläuft. Über Zeit zu sprechen heißt, in Bildern zu sprechen. Denn was genau ist Zeit? Erlebt ein Kind sie so wie ein Erwachsener? Warum fließt sie zäh wie Honig dahin, wenn wir uns langweilen, und zerrinnt im Alter wie Sand zwischen den Fingern? Warum und wie verfliegt die Zeit? In seiner ebenso leichtfüßigen wie tiefgr...
The Hudson River Estuary, first published in 2006, is a scientific biography with relevance to similar natural systems.
Biochemistry and ecology of biofilms from industrial, medical and other viewpoints.
Presenting the main concepts, this book leads students as well as advanced researchers from different disciplines to an understanding of current ideas in the complex field of comprehensive experimental investigation of biological objects, analysis of data, development of models, simulation, and hypothesis generation. It provides readers with guidance on how a specific complex biological question may be tackled: - How to formulate questions that can be answered - Which experiments to perform - Where to find information in databases and on the Internet - What kinds of models are appropriate - How to use simulation tools - What can be learned from the comparison of experimental data and modeling results - How to make testable predictions. The authors demonstrate how mathematical concepts can illuminate the principles underlying biology at a genetic, molecular, cellular and even organism level, and how to use mathematical tools for analysis and prediction.
Now in widespread use, generalized additive models (GAMs) have evolved into a standard statistical methodology of considerable flexibility. While Hastie and Tibshirani's outstanding 1990 research monograph on GAMs is largely responsible for this, there has been a long-standing need for an accessible introductory treatment of the subject that also emphasizes recent penalized regression spline approaches to GAMs and the mixed model extensions of these models. Generalized Additive Models: An Introduction with R imparts a thorough understanding of the theory and practical applications of GAMs and related advanced models, enabling informed use of these very flexible tools. The author bases his ap...