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Redox and Nitrosative Signaling in Cardiovascular System: from Physiological Response to Disease
The role of ROS/RNS signaling in cardiovascular functions and diseases is increasingly emerging in the last decades. The involvement of ROS/RNS in the control of a large number of cardiovascular functions like the regulation of the vascular tone, the control of blood pressure or myocyte excitation-contraction coupling and force development has been broadly investigated and in part clarified. On the other hand, many efforts have been focused in clarifying the redox mechanisms involved in cardiovascular diseases like ischemia/reperfusion injury, diabetes-associated cardiovascular dysfunctions, atherosclerosis or hypertension, just to mention the major ones. However, in most cases the two level...
Hot topics in Cardio-Oncology
Over the last years, thanks to growing advances in the field of cancer therapies, a considerable decrease in cancer mortality has been observed. Unfortunately, such therapies have shown a wide spectrum of cardiotoxicities. This book provides the readers with the latest advances and insights in the ever-expanding field of Cardio-Oncology. Specific topics discussed in the book include the potential role of inflammation in Cardio-Oncology and the description of the different manifestations of cardiotoxicities (including vascular toxicity, systemic hypertension, arrhythmias), analyzing the complex relationships between cancer and heart failure, two conditions whose prevalence increases with ageing. Furthermore, the role of biomarkers and imaging in cardio-oncology is discussed.
Microdomains in the Cardiovascular System
The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future.This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology.
La natura giusprivatistica delle tecniche alternative di risoluzione delle controversie
Le problematiche connesse all’introduzione di procedimenti conciliativi nel nostro sistema non possono ridursi alla sola verifica della funzionalità del modello negoziale, ma devono ricomprendere una delicata indagine sulla compatibilità giuridica dei sistemi alternativi con i principi fondamentali dell’ordinamento italiano e con quelli della Costituzione Repubblicana. In via generale la conciliazione può essere definita come uno strumento di composizione delle controversie rimesso alla volontà delle parti, con l’intervento di un terzo, finalizzato a provocare l’incontro delle volontà delle parti. La conciliazione non costituisce una figura negoziale a se, specificatamente disci...
Bacterial Flora in Digestive Disease
Hundreds of bacterial species make up human gut flora. The intestine has at least 400 different species of bacteria totaling over 1012 organisms. Of these, 99% are anaerobic bacteria. The gastrointestinal tract is then exposed to countless numbers of bacterial species and foreign antigens and has embedded a unique and complex network of immunological and non-immunological mechanisms to protect the host from potentially harmful pathogens. Healthy individuals are generally tolerant to their own microbiota, but such tolerance is impaired in patients with both organic and functional gastrointestinal diseases. The advancement of the knowledge on microbial-gut interactions in health and disease ha...
Diplomatic List
Contains the names of the members of the diplomatic staffs of all foreign missions to the U.S. and their spouses, listed in alphabetical order by country. Members of the diplomatic staff are the members of the staff of the mission having diplomatic rank. The report also includes a chronological list of national holidays around the world; a list of diplomats in order of precedence and date of presentation of credentials; and web site and e-mail addresses of embassies.
Sustainable Postharvest Technologies for Fruits and Vegetables
Fruits and vegetables, commonly termed as "fresh produce" are an important component of the human diet, as these provide various beneficial and essential health-related compounds. Nevertheless, fresh produce is susceptible to postharvest deterioration and decay along with loss of certain nutrients due to innapropriate storage conditions and lack of standard postharvest technologies. In addition, the short shelf life is considered another major constraint that must be extended after harvest to ensure a wider availability window of the fresh produce for consumers. From this perspective, the use of postharvest approaches is considered imperative to reduce the deterioration of harvested fresh pr...
Diplomatic List
Directory of foreign diplomatic officers in Washington.
Augmented Environments for Computer-Assisted Interventions
This book constitutes the refereed proceedings of the International Workshop on Augemented Environments for Computer-Assited Interventions, held in conjunction with MICCAI 2011, in Toronto, Canada, in September 2011. The 13 revised full papers presented were carefully reviewed and selected from 21 submissions. The papers cover the following topics: image registration and fusion, calibration, visualisation and 3D perception, hardware and optical design, real-time implementations, validation, clinical applications and clinical evaluation.
Concussion and Traumatic Encephalopathy
Readers will discover how very recent scientific advances have overthrown a century of dogma about concussive brain injury.
