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The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.
This book focuses on how to induce clinical arrhythmias in the electrophysiology (EP) laboratory, a procedure that is indispensable for analyzing the underlying mechanisms, and identifying the most effective treatment of the arrhythmia. In the main part of the book, the authors share their own experiences with 13 different medications that can be injected or infused for arrhythmia induction – ranging from isoprenaline and atropine to ephedrine – all of which can be easily found in any cardiology department. Each chapter begins with a description of the drug’s chemical structure and mechanism of actions, then illustrates the infusion preparation, dosage and side effects and lastly analyzes its electrophysiological properties and highlights the most important clinical studies on it. For each drug the authors list – in dedicated tables – administration protocols from their own hospital. This book is of interest to postgraduate students, cardiology residents, cardiologists and pediatric cardiologists with special interest in arrhythmias, as well as to trainees, technicians and nurses involved in the EP lab.
The objective of this book is to provide the fundamental comprehension of a broad range of topics in an integrated volume such that readership hailing from diverse disciplines can rapidly acquire the necessary background for applying it in pertinent research and development field.
"This unique monograph provides an in-depth account of the interactions between endothelial cells and their products with vascular smooth muscle -- highlighting how endothelial-derived products influence vascular tone and regulation of blood flow, including platelet aggregation. "
Summary This book is a definitive overview of the current 'state of the art' in cell biology. It is based on papers presented by leading researchers at the Spanish Society for Cell Biology's XIV Congress - a Congress that strives to achieve scientific excellence. Each participant was asked to prepare a 'mini review' of current and likely future development in their area of research. This book is based on those reviews. As such, it is therefore an analysis of current and future trends. Key Features Contains contributions from some of the world's leading researchers. The book is multidisciplinary, covering almost all topics in cell biology: from basic to applied cell biology, and a wide variet...
Nanobiophysics is a new branch of science that operates at the interface of physics, biology, chemistry, material science, nanotechnology, and medicine. This book is the first one devoted to nanobiophysics and introduces this field with a focus on some selected topics related to the physics of biomolecular nanosystems, including nucleosomal DNA and
The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations