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Bone Marrow T Cells at the Center Stage in Immunological Memory
Increasing evidence supports the notion that bone marrow (BM) represents a relevant player in T cell responses, particularly in its role as a specialized organ for long-term memory. Memory T cells are enriched in the BM over long times after priming, and can be recruited to the periphery upon antigenic challenge. The articles in this research topic include discussions of whether these T cells are passing-through or truly resident, as well as a debate on the extent of proliferation of BM memory T cells. Original research articles in this collection include an analysis of the number of memory T cells found in different bones as well as effects of B cell depletion on T cell memory in the BM. T cells in the BM can influence a number of processes, from bone remodeling, control of cancer, to effects on hemopoiesis or Graft versus Host Disease (GVHD). This research topic contains several contributions to these topics including discussions on how to translate BM T cell knowledge into medicine.
Her Story! A Tribute to Italian Women
A unique book! Italian women at their best! What talent! This book is a must read for everyone who loves Italian culture and those who appreciate talented women. Extensively researched with hundreds of references, it is a comprehensive encyclopedic analysis highlighting the length and breadth of Italy’s most incredibly talented women, including 114 writers, 56 opera singers, 63 other singers, 55 musicians, 52 film icons, 39 fashion designers, 59 medical women, 40 chefs, 47 artists, 23 academics and 114 sportswomen, amongst others. All discussed in chronological order in each of their fields with many interesting stories, including a chapter on the emigration of impressive female Italian talent.
Contemporary Challenges in Immunologic Testing in Clinical and Research Laboratories
Along the last several decades, it has been progressively appreciated that immunology plays an overwhelming role in the physiology and pathophysiology of most organs, tissues, and biological systems in multicellular organisms. Accordingly, several immunological parameters are used in research and clinical laboratories with the purpose of investigating, diagnosing, and monitoring a variety of pathological conditions. The rapidly evolving field of laboratory testing in immunology poses several challenges to professionals working in research and clinical laboratories, medical practice, educational activities, in vitro diagnostic industry, and regulatory agencies. Regular analytes, such as album...
Serafino Zappacosta and the Ceppellini School: A Pioneer Model For Nurturing Education in Immunology
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
Saints
Start each day with this beautifully illustrated gift book on 365 saints in the Christian heritage. Organized by saints’ specific feast days, each page of this beautifully illustrated book provides a day’s worth of history, tradition, and inspiration from the lives and teachings of the saints in the Christian canon, from St. Apollonia to St. Zita. This illustrated book of days tells the life stories, ministry, and beatification of 365 Saints, each beautifully rendered with classic paintings and historic iconography. Designed to become a family heirloom, this reference book lists each saint’s common patronages so readers can call upon them with prayers for intercession during times of trouble, sickness, or loss. A perfect gift for Christenings, Confirmations, birthdays, and holidays.
Innate Immune Cell Determinants of T Cell Immunity: From Basic Mechanisms to Clinical Implications
Long-lasting T cell immunity is delivered by an array of individual T lymphocytes expressing clonally distributed and highly specific antigen receptors recognizing an almost infinite number of antigens that might enter in contact with the host. Following antigen-specific priming in lymphnodes, naïve CD4 and CD8 T lymphocytes proliferate generating clones of effector cells that migrate to peripheral tissues and deliver unique antigen-specific effector functions. Moreover, a proportion of these effector lymphocytes survive as memory T cells that can be rapidly mobilized upon new exposure to the same antigen, even years after their primary induction. Innate immune cells play crucial roles in t...
