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Netherlandish Books offers a unique overview of what was printed during the fifteenth and sixteenth centuries in the Low Countries. This bibliography lists descriptions of over 32,000 editions together with an introduction and indexes.
This book presents up-to-date information on one of the hottest topics in prostate cancer, namely bone metastases. The most recent developments with respect to biology, pathology, diagnosis, and treatment are described, providing readers with an excellent understanding of the mechanisms of metastasis formation, the characteristics of metastases, their aggressiveness, and prognostic factors for treatment response. The coverage includes discussion of all of the best available options (laboratory, radiology, and nuclear medicine) for achieving early diagnosis and both established and novel therapeutic approaches. Detailed information is provided on hormonal manipulations, bone-targeted agents, vaccines, taxanes, and other treatments that are enriching the therapeutic armamentarium. The editors can be considered leaders in the field, with great experience in diagnostic and clinical oncology and research, and the authors are experts in diverse specialties. This ensures a multidisciplinary approach, mirroring the current situation in which treatment in patients with bone metastases is undertaken by a team of specialists and health professionals in a variety of fields.
This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the im...
In the last decade, the clinical management of melanoma has become more effective: basic clinical studies, randomized clinical trials, and new drugs have greatly improved the prognosis of patients, both in the initial and in the advanced stage of the disease. This book offers a wide and up-to-date overview of the multidisciplinary treatment of melanoma. Among the topics discussed, there are the role of sentinel lymph node biopsy and the radical dissection, following the results of international randomized clinical trials, in particular MSLT-II. The last chapters are focused on new medical treatments in adjuvant, neoadjuvant, and metastatic settings. The volume has been written for all the professionals involved in melanoma treatment, such as general surgeons, surgical oncologists, medical oncologists, dermatologists, radiotherapists, and nuclear medicine physicians.
Since the first edition of this book was published, much new knowledge has been gained on hemangiomas and vascular malformations. This revised and updated second edition, written by worldwide leaders in the field, fully reflects this progress. Important improvements in the treatment of hemangiomas are reviewed, including the use of beta-blockers and other medical therapies as well as advances in interventional treatments and the treatment of hemangiomas in specific locations. Vascular malformations are being investigated with increasing frequency all over the world and new challenges are emerging regarding both diagnosis and treatment. This edition considers the current role of the full rang...
Despite the fact that, if only by number, small and peripheral cities played an important role in fifteenth and sixteenth-century European print culture, book history has mainly been dominated by monographs on individual big book centres. Through a number of specific case studies, which deploy a variety of methods and a wide range of sources, this volume seeks to enhance our understanding of printing and the book trade in small and peripheral European cities in the fifteenth and sixteenth centuries, and to emphasize the necessity of new research for the study of print culture in such cities.
The second edition of this book serves as a central source of theoretical and practical knowledge to optimize the evaluation and treatment of patients with lymphedema. The book covers all aspects of the disease from anatomical and histological features to diagnosis as well as physical/medical and surgical management of the disease. Updated from the first edition to reflect the substantial progress in diagnostics, medical care and surgical intervention for this patient population, this volume has been reorganized to meet today’s practice requirements. It addresses the challenges faced by clinicians in the management of chronic lymphedema enabling them to meet the medical needs of this large patient community. Edited by world leaders in Vascular Medicine and Surgery, this comprehensive volume provides clear, concise background and recommendations in an easy-to-use format. It is a valuable reference tool for clinical practitioners (physicians/nurse practitioners/technicians) who wish to deliver state-of-the-art health care to their patients with lymphatic and venous disorders.
Thoroughly updated to reflect the latest research, discoveries, and practices in this fast-changing field, Principles and Practice of Lymphedema Surgery, 2nd Edition, provides thorough, step-by-step guidance to incorporate or expand the treatment of lymphedema in your practice. Written and edited by world-renowned experts in the field of lymphedema and microsurgery, this highly visual reference helps deepen your understanding of each procedure and how to perform them. From preoperative assessment to postoperative care, you’ll find authoritative instruction that equips you to implement the most innovative and latest surgical and nonsurgical approaches and achieve optimal outcomes for your p...