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Sildenafil, for the treatment of erectile dysfunction, is one of the first products that has made its way successfully from basic NO (nitrous oxide) research, to clinical routine therapy. Sidenafil, part of the Milestones in Drug Therapy series, presents the major breakthroughs in the field of NO physiology and pharmacology that led to the development of the drug, as well as clinical applications in one source guide. Written by leading experts in the field, each chapter covers aspects of clinical use and experience, pharmacokinetics, pharmacodynamics, biochemistry, and cultural science.
The essays in this volume are concerned with early printed narrative texts in Western Europe. The aim of this book is to consider to what extent the shift from hand-written to printed books left its mark on narrative literature in a number of vernacular languages. Did the advent of printing bring about changes in the corpus of narrative texts when compared with the corpus extant in manuscript copies? Did narrative texts that already existed in manuscript form undergo significant modifications when they began to be printed? How did this crucial media development affect the nature of these narratives? Which strategies did early printers develop to make their texts commercially attractive? Which social classes were the target audiences for their editions? Around half of the articles focus on developments in the history of early printed narrative texts, others discuss publication strategies. This book provides an impetus for cross-linguistic research. It invites scholars from various disciplines to get involved in an international conversation about fifteenth- and sixteenth-century narrative literature.
This book introduces the theoretical elements at the basis of various classes of algorithms commonly employed in the physical layer (and, in part, in MAC layer) of wireless communications systems. It focuses on single user systems, so ignoring multiple access techniques. Moreover, emphasis is put on single-input single-output (SISO) systems, although some relevant topics about multiple-input multiple-output (MIMO) systems are also illustrated. Comprehensive wireless specific guide to algorithmic techniques Provides a detailed analysis of channel equalization and channel coding for wireless applications Unique conceptual approach focusing in single user systems Covers algebraic decoding, modulation techniques, channel coding and channel equalisation
This book combines concise descriptions of the various andrological surgical interventions in the adolescent and adult with detailed analysis of the pre- and postoperative psychosexual counseling of the patient and his family that is appropriate to each procedure. It offers a multidisciplinary approach to the candidate for andrological surgery that reflects the everyday experiences of an andro-sexology team. Each chapter focuses on a particular surgical procedure. Succinct description of the disease and its epidemiology, diagnosis, and treatment is followed by extensive discussion of all aspects of psychosexual relevance and the required counseling. Topics addressed include, for example, the impact of diagnosis, body image issues, fears relating to the surgical procedure and its outcome, the risk of excessive expectations and consequent disillusionment, relationship issues and communication problems, and the role of the sexologist. The analysis and guidance offered in this book will be of particular value to the less experienced andrologist and will assist in achieving postoperative patient satisfaction.
This new Companion provides a broad and perceptive overview of the most important vernacular literary genre of the Middle Ages. Freshly commissioned, original chapters from seventeen leading scholars introduce students and general readers to the form's poetics, narrative voice and manuscript contexts, as well as its relationship to the Mediterranean world, race, gender and the emotions, among many other topics. Providing fresh perspectives on the first pan-European literary movement, essays range across a broad geographical area, including England, France, Italy, Germany and the Iberian Peninsula, as well as a varied linguistic spectrum, including Arabic, Hebrew and Yiddish. Exploring the celebration of chivalric ideals and courtly refinements, the volume excavates the tensions and traumas lying beneath decorous surface appearances. An introduction, bibliography of texts and translations as well as chapter-by-chapter reading lists complete this essential guide.
The horizons of laparoscopic surgery are expanding, such that the overwhelming majority of abdominal urologic procedures have now been performed laparoscopically. In some of these procedures, the laparoscopic alternative has been demonstrated to be superior to its open counterpart; in others comparative analyses are ongoing; and in yet others, only the initial forays into minimally invasive surgery have been undertaken. This book sets out to collate the current body of knowledge on laparoscopic urology under one cover. The authors are respected experts in the field and have provided concise, thoughtful updates on their respective topics. The information contained in this volume will help urologists to increase their laparoscopic knowledge and skills.
First English translation of one of the most influential French poems of the Middle Ages. The anonymous Ovide moralisé (Moralized Ovid), composed in France in the fourteenth century, retells and explicates Ovid's Metamorphoses, with generous helpings of related texts, for a Christian audience. Working from the premise that everything in the universe, including the pagan authors of Graeco-Roman Antiquity, is part of God's plan and expresses God's truth even without knowing it, the Ovide moralisé is a massive and influential work of synthesis and creativity, a remarkable window into a certain kind of medieval thinking. It is of major importance across time and across many disciplines, includ...
Based on the highly successful first edition of Prostate Biopsy: Indications, Techniques, and Complications, this new volume presents new concepts that have emerged in answer to current questions from its audience. Many new perspectives and technologies are presented, many from the authors’ internationally recognized work on the topic. Substantial developments in techniques and complications are explored in detail. The chapter authors comprise a complete spectrum of specialists in their respective subject areas. All authors are internationally accepted as the premier authorities on their chosen topics. Prostate Cancer Diagnosis: PSA, Biopsy, and Beyond presents new data on the controversial issue of PSA screening and thresholds as indication to perform biopsy. Office based transrectal saturation biopsy is covered in detail. Other topics explored include template guided biopsy and image-guided biopsy as well as a completely new paradigm for prevention of complications. Prostate Cancer Diagnosis: PSA, Biopsy, and Beyond will be of great value and utility to all practicing urologists.
This book provides a concise overview of the latest controversies and advances in men’s health. It covers the male anatomy, physiology, and the metabolic syndromes that most commonly affect males. A range of benign and malignant conditions affecting the prostate, testes, rectum and colon are detailed. Chapters feature an easy-to-follow format and feature learning objectives to highlight the key concepts in each chapter aiding the reader to develop a thorough understanding of fundamental aspects in men’s health. Men’s Health and Wellbeing features insightful reviews of controversies and recent developments in men’s health, and is a valuable resource for all trainee and practicing medical professionals who treat these patients.
Artists and the public alike have always been fascinated by obscene imagery. The Obscene, however, is difficult to define. One of the earliest interpretations is of Greek origin and argues that the word derives from "ob skene", indicating the space behind the stage or scene. "Off-scene" remains what should be hidden from public view, be it morally questionable, offensive, disgusting or unbearable to look at. This book presents a collection of essays that cast light on some "Scene of the Obscene" in art and visual culture from the Middle Ages to today, taking into consideration the malleable nature of socio-cultural assumptions and theoretical reflections on the topic.The contributions focus on historically distinct artistic acts and social sites where established cultural categories and legal norms are violated, with artists and publishers deliberately breaking moral taboos and offending the public taste. They discuss how society reacted to these transregressions and how obscenity and its conceptions shape the face of their respective time.