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This book is a printed edition of the Special Issue entitled “Anticancer Agents: Design, Synthesis and Evaluation” that was published in Molecules. Two review articles and thirty research papers are included in the Special Issue. Three second-generation androgen receptor antagonists that have been approved by the U.S. FDA for the treatment of prostate cancer have been reviewed. Identification of mimics of protein partners as protein-protein interaction inhibitors via virtual screening has been summarized and discussed. Anticancer agents targeting various protein targets, including IGF-1R, Src, protein kinase, aromatase, HDAC, PARP, Toll-Like receptor, c-Met, PI3Kdelta, topoisomerase II, ...
In 1968, ten thousand students marched in protest over the terrible conditions prevalent in the high schools of East Los Angeles, the largest Mexican community in the United States. Chanting Chicano Power, the young insurgents not only demanded change but heralded a new racial politics. Frustrated with the previous generation's efforts to win equal treatment by portraying themselves as racially white, the Chicano protesters demanded justice as proud members of a brown race. The legacy of this fundamental shift continues to this day. Ian Haney Lopez tells the compelling story of the Chicano movement in Los Angeles by following two criminal trials, including one arising from the student walkou...
The Op-Ed Novel follows a clutch of globally renowned Spanish novelists who swept into the political sphere via the pages of El País. Their literary sensibility transformed opinion journalism, and their weekly columns changed their novels, which became venues for speculative historical claims, partisan political projects, and intellectual argument.
"Teresa Lozano Long Institute of Latin American Studies."
Meu olhar sobre temas relevantes do ensino superior após reflexão e experiências vividas no ensino, pesquisa, extensão e gestão acadêmicas. Boa leitura
La Conadep fue creada por el Poder Ejecutivo Nacional en diciembre de 1983 con el objetivo de intervenir activamente en el esclarecimiento de los hechos relacionados con la desaparición de personas, ocurridos en el país. El Nunca más es un claro testimonio de la necesidad de nuestra sociedad de conservar vigente el doloroso recuerdo de la época más oscura que ha conocido la historia nacional; es una demostración de que a lo largo de los años que nos separan de aquel trágico período, la comunidad argentina no ha querido distanciarse de su historia, por mucho que sea el horror que despierte su recuerdo. Es necesario más que nunca reafirmar la consigna que el pueblo argentino hizo suya a partir del título de este libro.