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Innate immunity has a critical role in the early stage of the host defense response by the timely recognition of pathogenic or danger signals by various cell surface or cytoplasmic receptors. This is followed by signal transduction via various adaptor and effector molecules. The main functions of innate immunity are to identify and remove the invading pathogens, to recruit various immune cells to the site of infection, and to prepare the adaptive immune response. The Innate immune system has been intensively studied for several decades and now we can begin to understand this system on a molecular level.
Tesis doctoral dirigida por Paul Preston en la London School of Economics (en inglés) sobre el fracaso del catalanismo durante el primer franquismo.
Bringing together a group of outstanding judges, scholars and experts with first-hand experience in the field of transitional justice in Latin America and Spain, this book offers an insider’s perspective on the enhanced role of courts in prosecuting serious human rights violations and grave crimes, such as genocide and war crimes, committed in the context of a prior repressive regime or current conflict. The book also draws attention to the ways in which regional and international courts have come to contribute to the initiation of national judicial processes. All the contributions evince that the duty to investigate and prosecute grave crimes can no longer simply be brushed to the side in...
Un lugar seguro es un juego entre el relato y la novela en el que se entrelazan cuatro historias. Cada una protagonizada por uno de sus cuatro personajes: Laura, Daniel, Íkar y Crispín van desarrollando la trama y poniendo foco en el fracaso laboral y el paro juvenil. Una obra que transcurre a lo largo de la crisis financiera que vivimos en la primera década del siglo XXI y donde podemos observar la soledad a la que se enfrentó la generación recién graduada en la universidad, la falta de oportunidades y el desarraigo. Cuatro historias, cada una de las cuales nos muestra una faceta de Laura, la persona sobre la que recae el peso de la obra.
¿Existe una identificación de las marcas de cerveza con su territorio? ¿Son las redes sociales digitales una herramienta útil para esta identificación? En las páginas de Territorio cerveza encontrarás la respuesta a estas preguntas. El autor llega a la conclusión de que las grandes cerveceras utilizan los valores de sus lugares de procedencia para generar mensajes positivos a través de las redes sociales: el cosmopolitismo madrileño para Mahou, el clima mediterráneo para Estrella Damm, la diversión sevillana para Cruzcampo y el carácter aventurero de San Miguel.
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The global reception of Samuel Beckett raises numerous questions: in which areas of the world was Beckett first translated? Why were Beckett texts sometimes slow to penetrate certain cultures? How were national literatures impacted by Beckett's oeuvre? Translating Samuel Beckett around the World brings together leading researchers in Beckett studies to discuss these questions and explore the fate of Beckett in their own societies and national languages. The current text provides ample coverage of the presence of Beckett in geographical contexts normally ignored by literary criticism, and reveals unknown aspects of the 1969 Nobel Prize winner interacting with translators of his work in a number of different countries.