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Severe Asthma
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
Conspicuous Destruction
Addressing two sets of concerns, this report covers both the abuses relating to the seventeen years of war between the Mozambique Armed Forces and the rebel Mozambique National Resistance, as well as the reforms instigated by the ruling Mozambique Liberation Front under President Joachim Chissano. Africa Watch evaluates the progress made by the Liberation Front government toward a democratic system of government that respects civil and political rights. The 1990 Constitution and related legislation are the centerpiece of this transition, and represent the most wholehearted attempt to build an institutional and legal framework to guarantee respect for human rights so far attempted in the history of Mozambique. Major concerns remain, however, relating to the ability of the government to implement the promised changes.
Inmigrantes en Europa
La mayoría de los Estados europeos limita el acceso al derecho a la protección de la salud a colectivos como el de los inmigrantes en situación administrativa irregular. Pero ¿es ético limitar la asistencia sanitaria a un colectivo? ¿No estaremos ante un problema bioético, concretamente de bioética social? El autor aborda en este ensayo las causas del crecimiento de la migración irregular y las políticas migratorias europeas, y estudia la integración social y la atención sanitaria a los inmigrantes, desmontando mitos y falsas creencias sobre su influencia en la insostenibilidad de los sistemas sanitarios, la atención primaria y la prestación sanitaria. Finalmente, plantea una deliberación bioética y establece los principios básicos y fundamentales sobre los que fundamentar el derecho a la salud: respeto a la dignidad humana, no maleficencia, justicia, protección frente a la vulnerabilidad, responsabilidad, compasión y solidaridad.
Loans and Credit in Consilia and Decisiones in the Low Countries (c. 1500-1680)
Based on consilia and decisiones, Wouter Druwé studies the multinormative framework on loans and credit in the Golden Ages of Antwerp and Amsterdam (c. 1500-1680). He analyzes the use of a wide variety of legal financial techniques in the Low Countries, such as money lending and the taking of interest, the constitution of annuities, cession and delegation, bearer bonds, bills of exchange, partnerships, and representation in financial affairs, as well as the consequences of monetary fluctuations. Special attention is paid to how the transregional European system of learned Roman and canon law (ius commune) was applied in daily ‘learned legal practice’. The study also deals with the prohibition against usury and with the impact of moral theology on legal debates.
La ingeniería genética
La tesis de la que parte esta disertación doctoral es que el principio de precaución aplicado a la ingeniería genética y de forma singular a cada técnica biomédica, garantiza una tutela de los derechos humanos o bioderechos porque gestiona los riesgos para las generaciones presentes y futuras derivados de la edición del genoma humano en diferentes momentos biológicos: línea germinal y línea somática, además confronta al derecho a la libertad de investigación imponiéndole límites razonables y proporcionales.
