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Non Pharmacological Therapies in the Management of Osteoarthritis
Osteoarthritis is a chronic disease prevalent among the elderly. Its most prominent feature is the progressive destruction of articular cartilage which results in impaired joint motion, severe pain and ultimately disability. Its prevalence and its impact on daily life pose a significant public health problem. Today, a cure for osteoarthritis remains elusive and the management of the disease is largely palliative, focusing on the alleviation of symptoms. Current recommendations include a combination of pharmacological and non-pharmacological treatments. The term “non-pharmacological” includes physical therapy and rehabilitation, but also nutraceuticals. All guidelines on osteoarthritis ma...
Mechanobiology
Over recent years, there has been increasing interest in the fundamental role played by local mechanical parameters in chondrocyte regulation and cartilage dysfunction as a first step in the development of osteoarthritis. This is how the idea of mechanobiology and the concept of mechanotransduction were born in the 90's. Indeed, a broad diversity of physiological phenomena is induced by mechanical stimuli (hearing, orientation to gravity, touch, tissue remodeling...) but the mechanism by which mechanical forces may regulate a physiological response is still unknown. In other respects, the concept of regenerative medicine has recently developed in parallel to this. Regenerative medicine is an...
Atlas of Osteoarthritis
This Atlas provides an up-to-date and comprehensive overview of the historical and current perspectives on osteoarthritis, including the pathophysiology and epidemiology of the disease. Written by leading authors in the field of osteoarthritis, the book discusses classification, etiology and risk factors for osteoarthritis, the disease course and determinants of osteoarthritis progression, clinical features and diagnosis as well as imaging methods to assess joint damage. The Atlas of Osteoarthritis concludes with the latest treatment updates including both nonpharmacological and pharmacological treatments, as well as surgical recommendations for patients with the disease. Osteoarthritis is the most common form of joint disease causing joint pain, stiffness, and physical disability among adults. It is an important issue for both the individual and society with its impact on public health continuing to grow as a result of the aging population, the rising prevalence of obesity, and the lack of definitive treatments to prevent or halt the progress of the disease.
WHO guideline for non-surgical management of chronic primary low back pain in adults in primary and community care settings
The purpose of the guideline is to provide evidence-based recommendations on nonsurgical interventions for chronic primary LBP (CPLBP) in adults, including older people, that can be delivered in primary and community care settings to improve CPLBP-related health and well-being outcomes. For this reason, the guideline does not consider interventions typically delivered in secondary or tertiary care settings (e.g. surgical or other invasive procedures) or workplace interventions. The target audience is health workers of all disciplines working in the primary and community care settings. In this context, the guideline is intended to be discipline neutral. The guidelines will be of use to clinical staff including medical doctors, nurses, allied health workers including chiropractors, occupational therapists, physiotherapists, pharmacists, psychologists and community health workers, as well as public health programme and system managers.
Randomized Clinical Trials of Nonpharmacological Treatments
Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable and non-implantable devices, rehabilitation, psychotherapy, and behavioral interventions. Unlike pharmacological treatments, these have no specific requirements for approval. Consequently, they can be widely proposed in clinical pra
Oxford Textbook of Osteoarthritis and Crystal Arthropathy, Third Edition
A trustworthy clinical companion, the textbook offers best practice and management strategies for these common joint diseases. Formerly published as Osteoarthritis, the extensively revised third edition of the Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides up-to-date and evidence-based guidance on how to assess, diagnose, and manage patients. A prestigious and international author team ensure information is expert and relevant-this is a practical tool for clinicians managing people with osteoarthritis, gout, and other crystal-associated arthritis. Confidently consider and chose the right blend of treatment for your patient, whether physical, pharmacological, surgical, or ...
Openwork
A career retrospective of poetry and prose works by one of the under-recognized giants of French literature André du Bouchet, a great innovator of twentieth-century letters, has yet to be fully recognized by a wide circle of international readers. This inviting volume sets out to remedy the oversight, introducing a selection of du Bouchet's poetry and prose to English-language readers through the brilliant translations of Paul Auster and Hoyt Rogers. Openwork showcases pieces from the author's entire trajectory, beginning with little-known pieces from the 1950s, followed by major poems from the 1960s, and concluding with works written or rewritten in the poet's later decades. Throughout his life, du Bouchet devoted himself to long walks in his beloved French countryside, jotting down entries in notebooks as he rambled. These notebooks--more than one hundred all together--have emerged as signal works in their own right, and their musings are well represented in this anthology.
Handbook of Anthropology in Business
The first comprehensive work on the burgeoning field of business anthropology, this innovative reference book, including more than 60 international scholar-practitioners, provides a foundation for the field for years to come.
A Textbook On ARTIFICIAL INTELLIGENCE IN PRECISION MEDICINE, DRUG DEVELOPMENT, AND HEALTHCARE
I would like to take this opportunity to expose you to the topic of "Artificial Intelligence in Precision Medicine, Drug Development, and Healthcare." Artificial intelligence (AI) is one of the most revolutionary forces that will shape the future of medicine and healthcare delivery, and this book is a comprehensive investigation of that force. In recent years, artificial intelligence has emerged as a strong technology that has the ability to revolutionise every area of the healthcare ecosystem. This includes personalized treatment plans, medication discovery and development, and even the delivery of healthcare services. At the convergence of artificial intelligence and precision medicine lie...
