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Parasites and Allergy
The inverse correlation between allergic diseases and helminth infections has been debated for over 30 years. It was initially assumed that the underlying mechanism is an imbalance between Th1 and Th2 responses that, as a result of reduced exposure to Th1-inducing infectious pathogens, has tipped to allergic Th2 responses. It has only recently been clearly demonstrated that helminth infections have negative effects on allergic disease manifestation. This was shown to be consistent with the activity of regulatory cell populations, which control the effector mechanisms of both Th1 and Th2. In th.
Role of CD1- and MR1-restricted T cells in Immunity and Disease
CD1 and MR1 are major histocompatibility complex (MHC) class I-related proteins that bind and present non-peptide antigens to subsets of T cells with specialized functions. CD1 proteins typically present lipid antigens to CD1-restricted T cells, whereas MR1 presents vitamin B-based ligands and a variety of drugs and drug-like molecules to MR1-restricted T cells. The CD1 family of antigen presenting molecules has been divided into two groups: Group 1 contains CD1a, CD1b and CD1c, and Group 2 contains CD1d. Additionally, CD1e is expressed intracellularly and is involved in the loading of lipid antigens onto Group 1 CD1 proteins. Humans express both Groups 1 and 2 CD1 proteins, whereas mice onl...
NKT Cells in Cancer Immunotherapy, 2nd Edition
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Change in Epidemiology and Etiology of Respiratory Tract and Gastrointestinal Infections during COVID-19 Pandemic
The COVID-19 pandemic has had a significant impact on the epidemiology and etiology of respiratory tract and gastrointestinal infections. The implementation of control measures such as social distancing and hand hygiene was associated with a decrease in the incidence of some respiratory and gastrointestinal infections caused by other viruses and bacteria. Epidemiological data suggest that the incidence of respiratory tract infections other than SARS-CoV-2 infection has decreased during the COVID-19 pandemic, possibly due to the adoption of several non-pharmaceutical interventions in public areas. Currently, there is very little research on the interaction between SARS-CoV-2 and other infecti...
Proceedings of 3rd International Conference on Influenza and Zoonotic Diseases 2017
August 21-22 2017 Birmingham,UK Key Topics : Zoonotic Diseases: Global Infectious Disease Burden, Pathogenicity of Influenza Virus, Types of Zoonotic Diseases and Transmission, Influenza Vaccines and Vaccinnation, Influenza: Causes, Symptoms and Treatment, Influenza Strains : Detection and Differentiation, Antiviral Drug Development and Treatment Strategies, Including Vaccination, Advances in Viral Detection and Identification Technologies, Host Genetics of Infection and Immunology, Evolution and Epidemiological Aspects of Influenza and Zoonotic Diseases, Neglected Tropical and Communicable diseases, Vaccines against Zoonotic Diseases, Tracking and Preventing Zoonotic Disease,
Genetics Abstracts
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Handbook of Dendritic Cells, 3 Volume Set
Dendritic cells play a key role in human immunoregulation. They are the most potent form of antigen presenting cells, often referred to as "pacemakers of the immune system". The properties of dendritic cells pave the way for multifaceted clinical applications: they can be used to step up immune response to tumor and infectious disease antigens and they are a valuable tool in transplantation medicine. Information available on these important cells continues to escalate, making it almost impossible for anyone working in the field to keep up with developments. This is the most comprehensive handbook on dendritic cells, opening with an introduction by Ralph M. Steinman and written by international experts. It covers all aspects from molecular cell biology to clinical applications and highlights the role of dendritic cells in fighting cancer, virus infections, and autoimmune diseases.
