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Specific operative and nonoperative techniques and their results are stressed. The book is extensively illustrated with drawings, most of which were made for this book, microscopy photos, and serial radiographs. The reader learns of pediatric orthopedic deformity in relation to normal and abnormal developmental biology, the worsening of untreated disease with growth, and the diagnostic and treatment interventions required based on the stage of progression.* Treatments are correlated with the pathologic state of the disorder* Discusses disorders from earliest onset to the final state showing how the altered biology leads to progressively greater clinical deformity* Initial chapter focuses on development bone biology stressing a broad based approach involving histologic, gene and molecular, and biomechanical features* Subsequent chapters discuss the pathogenesis of the various deformities, natural history, radiographic and imaging findings and orthopaedic and surgical management
A revised, enlarged, and updated edition of this authoritative and entertaining reference book —named the #2 essential home library reference book by the Wall Street Journal “Shapiro does original research, earning [this] volume a place on the quotation shelf next to Bartlett's and Oxford's.”—William Safire, New York Times Magazine (on the original edition) “A quotations book with footnotes that are as fascinating to read as the quotes themselves.”—Arthur Spiegelman, Washington Post Book World (on the original edition) Updated to include more than a thousand new quotations, this reader-friendly volume contains over twelve thousand famous quotations, arranged alphabetically by a...
Volume 2 of this comprehensive and state-of-the-art text on pediatric orthopedic deformities focuses on conditions of the lower extremity. Developmental disorders of the hip – developmental dysplasia of the hip (DDH), Legg-Calvé-Perthes disease (LCP), coxa vara including slipped capital femoral epiphysis (SCFE), and femoroacetabular impingement (FAI) – the knee, the ankle and foot, as well as rotational and angular deformities of the lower limb are discussed in detail. Presentation for each deformity includes: definition, detailed review of the pathoanatomy, experimental biological investigations (where applicable), natural history, review of the evolution of diagnostic and treatment te...
A presentation of general results for discussing local optimality and computation of the expansion of value function and approximate solution of optimization problems, followed by their application to various fields, from physics to economics. The book is thus an opportunity for popularizing these techniques among researchers involved in other sciences, including users of optimization in a wide sense, in mechanics, physics, statistics, finance and economics. Of use to research professionals, including graduate students at an advanced level.
Blood loss in spine surgery is a significant and very common problem connected with all kinds of surgical procedures. An international faculty of authors provide a comprehensive survey on the research and evidence about blood sparing in spine surgery. This publication fills a gap in the spinal literature and provides invaluable data for all those confronted with blood loss during surgical procedures on the spine.
Developmental biology of normal bone and cartilage including histogenesis, molecular/gene and biomechanical aspects is updated and expanded. The book outlines the biology of: bone repair with differing mechanical environments; cartilage repair at articular and physeal sites; and distraction osteogenesis. The generously illustrated text provides an in-depth presentation of the interplay between normal developmental biology, abnormal pathologic states and the influence of operative and non-operative orthopedic interventions on childhood orthopedic deformity. Thirty-four principles underlying the development, progression and management of skeletal deformity in the growing child are defined. Ort...
Written by a panel of world authorities, this comprehensive text is the only book of its kind, covering the full range of neuromuscular diseases seen in children. It explains how childhood neuromuscular diseases differ from those in adult patients, and it provides clinicians with all the knowledge they need to successfully diagnose and treat their pediatric patients.
The proceedings of the Third International Conference (on title) held in Chatham, Mass., October, 1988. Presents coverage of many areas of the skeletal system, including new experimental techniques, research areas, ideas, and hypotheses. Discusses at length the chemical nature and structure of organic matrix components and their influence with respect to regulation of cell function. Annotation copyrighted by Book News, Inc., Portland, OR
This book presents results obtained from the whole mount preparations, radiological, and histological studies of 60 pu/pu and pu/+ mice from late embryo until 3 months of age. Most mice were in the embryo to 6 week age group where vertebral developmental changes are most marked. Although vertebral abnormalities have been identified as due to mutations in the delta-like 3 (Dll3) gene, it is evident that each mouse has differing structural abnormalities. The disorder is analogous to human congenital scoliosis, a common variant of which is spondylocostal dysplasia. The histological studies presented in this book include plastic embedded sections which allow for high level resolution not only of vertebrae, intervertebral discs, and ribs but also of associated spinal cord, nerve roots and ganglia. In addition an overview of embryo and neonatal development in mouse, chick and human vertebrae is provided to better assess how and where deviant pathoanatomy occurs. The book discusses the possible variables involved in creating final deformity beyond the gene abnormality itself.