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Vaccination Strategies of Tropical Diseases
This work in the field of tropical medicine provides an in-depth review in the development of vaccines against some of the most debilitating tropical diseases. In this multi-contributed, three-part book, with clear and ample illustrations, the reader will gather useful data and guidance to further his study in the field.
Advances in Parasitology
This volume of Advances in Parasitology has a predominantly protozoological flavor. - The questionable pathogenicity of Blastocytis, a ptorist closely related to amoeboflagellates - Discussion of Giardia and the evidence of early branching of the eukaryotic stem - Full overview of current knowledge of the immunology of Leishmania - Explanation of the way trypanosomatids transport nutrients and ions across their membranes - A review of the biology of the coccidian parasites of fish with extensive illustrations - A review of the sexuality of parasitic crustaceans
T-Cell Paradigms in Parasitic and Bacterial Infections
It has been said that the development of vaccines against a variety of infectious diseases is among the greatest triumphs of immunology. Indeed, several pathogens have lost their horror through the availability of effective vaccination measures. Unfortunately, this does not hold true for the pathogens dealt within this volume. Malaria, schistosomiasis, leishmaniasis, leprosy, and tuberculosis together are prevalent in more than 100 countries, and over 400 million persons suffer from these diseases. It is becoming increasingly clear that the failure to control these infections in a satisfactory way is directly related to the complexity oftheir interactions with the immune system. These agents...
T-Cell Subsets and Cytokines Interplay in Infectious Diseases
Presenting a wealth of new data on the interaction among T-cell subsets and cytokines, this book offers a fresh perspective on infectious diseases. It provides useful insights into the nature and treatment of helminthic and mycobacterial infections, with special emphasis on leprosy, leishmaniasis, malaria and trypanosomiasis. The outcome of the host response to infectious agent is seen as depending upon the T-cell subsets activated and the cytokines produced by them and other cells, such as macrophages, B cells and basophils. Experts contributions shed new light on how TH0 cells are preferentially activated and differentiated into TH1 or TH2 subsets; TH1 and TH2 cells and their cytokines induce both protective immune responses and adverse immune reactions to infectious agents; cytokines modulate the response of infectious diseases to chemotherapy; and cytokines, their receptors and antagonist, and anti-cytokine antibodies can be used in therapy. Those working in the fields of immunology, parasitology, microbiology and vaccine development particularly if they are interested in tropical diseases, will find the volume an invaluable source of information.
T Cell Subsets in Infectious and Autoimmune Diseases
T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents up-to-the-minute data on the role of T cells in autoimmune diseases.
Stress Response in Pathogenic Bacteria
The ability of pathogenic bacteria to adapt to various chemical, biochemical and physical conditions within the human host and their ability to respond to stresses generated in these environments is a central feature of infectious diseases and the outcome of bacterial infection. This book covers the key aspects of this rapidly developing field, including the generation of stresses by the host immune system, bacterial response to reactive chemicals, and adaptation to environmental conditions of anatomical niches such as the gut, mouth and urogenital tract. It also addresses the increasing impor.
Intracellular Parasites
Volume 18 of the Subcellular Biochemistry series, which specializes in various aspects of the biochemistry of the intracellular parasites, was initially proposed by Jose Luis Avila and strongly supported by myself, as Series Editor of Sub cellular Biochemistry. Considerable assistance was received from Professor Frank Wunderlich (University of Dusseldorf) and more particularly from Dr. Michael Miles (London School of Hygiene and Tropical Medicine) during the compilation of the list of possible chapters. Our initial aim was to present a comprehensive survey of this broad field of study. Although some interesting topics have been lost due to authors backing out late in the production schedule of the book, the manuscripts that were submitted have provided a useful over view of the subject, with notable strength within the field of Leishmania. The 13 chapters of the book have been grouped according to subject. The first five chapters deal with Leishmania and are followed by two chapters on Try ponosoma cruzi, two on the malarial parasites, and two on the Coccidia. The fmal two chapters cover the Microsporidia and chemotherapy, respectively.
Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques
Today's drug research is an extremely complex process which, apart from chemistry, pharmacology, toxicology and preclinical trials, in cludes a variety of sciences such as biotechnology, biochemistry, im munology, physics, biology and even computer sciences. The Table of Contents of the present volume demonstrates this situation and makes it evident that the individual researcher cannot possibly hope to keep abreast of all aspects of modern drug research. In this re spect, the series of monographs "Progress in Drug Research" pro vides valuable help and assistance. Those who simply wish to remain informed of the latest trends and developments in drug research can use the 34 volumes so far ava...
Metal Ions in Biological Systems
Continues the tradition of excellence established in previous volumes in this acclaimed series. Volume 36 focuses on the vibrant research area concerning the interrelation between free radicals and metal ions and their resulting effects on life processes; it offers an authoritative and timely account of this fascinating area of research in 21 chapters.
Immunology of Intracellular Parasitism
Intracellular prokaryotic and eukaryotic organisms cause some of the most intractable problems in the fields of human and animal infectious diseases. Such infections are characteristically long and chronic and accompanied by deleterious immunopathological changes. The nine chapters in this volume, all written by internationally acknowledged experts in their fields, explore the immunological features common to representative intracellular organisms and also the special features whereby particular species evade immune attack and how they are destroyed with special reference to experimental and human listeriosis, tuberculosis, leishmaniasis, toxoplasmosis, African and American trypanosomiasis, ...
